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Article
Supercooling extends preservation time of human livers
The inability to preserve vascular organs beyond several hours contributes to the scarcity of organs for transplantation1,2. Standard hypothermic preservation at +4 °C (refs. 1,3) limits liver preservation to les...
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Article
Open AccessCell release during perfusion reflects cold ischemic injury in rat livers
The global shortage of donor organs has made it crucial to deeply understand and better predict donor liver viability. However, biomarkers that effectively assess viability of marginal grafts for organ transpl...
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Article
Subzero non-frozen preservation of human livers in the supercooled state
Preservation of human organs at subzero temperatures has been an elusive goal for decades. The major complication hindering successful subzero preservation is the formation of ice at temperatures below freezin...
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Article
Open AccessPartial freezing of rat livers extends preservation time by 5-fold
The limited preservation duration of organs has contributed to the shortage of organs for transplantation. Recently, a tripling of the storage duration was achieved with supercooling, which relies on temperatu...