123 Result(s)
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Article
Open AccessRadiomics of pericardial fat: a new frontier in heart failure discrimination and prediction
To use pericardial adipose tissue (PAT) radiomics phenoty** to differentiate existing and predict future heart failure (HF) cases in the UK Biobank.
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Open AccessNHS Health Check attendance is associated with reduced multiorgan disease risk: a matched cohort study in the UK Biobank
The NHS Health Check is a preventive programme in the UK designed to screen for cardiovascular risk and to aid in primary disease prevention. Despite its widespread implementation, the effectiveness of the NHS...
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Open AccessGenome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure
We conduct a large-scale meta-analysis of heart failure genome-wide association studies (GWAS) consisting of over 90,000 heart failure cases and more than 1 million control individuals of European ancestry to ...
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Open AccessPrediction of incident cardiovascular events using machine learning and CMR radiomics
Evaluation of the feasibility of using cardiovascular magnetic resonance (CMR) radiomics in the prediction of incident atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI), and stroke using...
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AI in the Real World
This chapter deals with important considerations to factor in when translating technical advances in AI to real clinical workflows. The importance of considering existing workflows is emphasized, including ide...
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Open AccessMulti-organ imaging demonstrates the heart-brain-liver axis in UK Biobank participants
Medical imaging provides numerous insights into the subclinical changes that precede serious diseases such as heart disease and dementia. However, most imaging research either describes a single organ system o...
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Open AccessAtrial fibrillation prediction by combining ECG markers and CMR radiomics
Atrial fibrillation (AF) is the most common cardiac arrhythmia. It is associated with a higher risk of important adverse health outcomes such as stroke and death. AF is linked to distinct electro-anatomic alte...
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Open AccessEstimation of biological heart age using cardiovascular magnetic resonance radiomics
We developed a novel interpretable biological heart age estimation model using cardiovascular magnetic resonance radiomics measures of ventricular shape and myocardial character. We included 29,996 UK Biobank ...
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Open AccessMinimising multi-centre radiomics variability through image normalisation: a pilot study
Radiomics is an emerging technique for the quantification of imaging data that has recently shown great promise for deeper phenoty** of cardiovascular disease. Thus far, the technique has been mostly applied...
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Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function
Right ventricular (RV) structure and function influence the morbidity and mortality from coronary artery disease (CAD), dilated cardiomyopathy (DCM), pulmonary hypertension and heart failure. Little is known a...
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Open AccessSociety for Cardiovascular Magnetic Resonance (SCMR) guidelines for reporting cardiovascular magnetic resonance examinations
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Article
Open AccessPrecision measurement of cardiac structure and function in cardiovascular magnetic resonance using machine learning
Measurement of cardiac structure and function from images (e.g. volumes, mass and derived parameters such as left ventricular (LV) ejection fraction [LVEF]) guides care for millions. This is best assessed usin...
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Open AccessImproving robustness of automatic cardiac function quantification from cine magnetic resonance imaging using synthetic image data
Although having been the subject of intense research over the years, cardiac function quantification from MRI is still not a fully automatic process in the clinical practice. This is partly due to the shortage...
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Open AccessEvidence-based cardiovascular magnetic resonance cost-effectiveness calculator for the detection of significant coronary artery disease
Although prior reports have evaluated the clinical and cost impacts of cardiovascular magnetic resonance (CMR) for low-to-intermediate-risk patients with suspected significant coronary artery disease (CAD), th...
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Chapter
Biobanks and Artificial Intelligence
Medicine and healthcare are beginning to witness the development of artificial intelligence (AI)-based techniques and tools that can address complex healthcare problems. Although these AI-based technologies ar...
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Health Economics, Economic Evaluation and Artificial Intelligence Technology
Health economics is the study of allocating scarce goods within a healthcare market. Due to constrained budgets, clinical effectiveness is not enough to inform healthcare planning and provision. Economic evalu...
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Open AccessBrain age estimation at tract group level and its association with daily life measures, cardiac risk factors and genetic variants
Brain age can be estimated using different Magnetic Resonance Imaging (MRI) modalities including diffusion MRI. Recent studies demonstrated that white matter (WM) tracts that share the same function might expe...
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Diagnosing excessive trabeculation cardiomyopathy: in pursuit of the “holy grail”
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Article
Open AccessVitamin D and coronavirus disease 2019 (COVID-19): rapid evidence review
The rapid global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has re-ignited interest in the possible role of vitamin D in ...
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Open AccessAdverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank
Coronavirus disease 2019 (COVID-19) disproportionately affects older people. Observational studies suggest indolent cardiovascular involvement after recovery from acute COVID-19. However, these findings may re...