17 Result(s)
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Article
Open AccessGentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis: a retrospective analysis
Listeria monocytogenes causes severe bacterial infections with the highest mortality rate among foodborne pathogens in Europe. Combination treatment with ampicillin and gentamicin is recommended for invasive mani...
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Article
Open AccessHigh burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022
Bacterial pneumonia, a major cause of respiratory tract infections (RTI), can be challenging to diagnose and to treat adequately, especially when seasonal viral pathogens co-circulate. The aim of this study wa...
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Article
Open AccessTecovirimat for the treatment of severe Mpox in Germany
In May 2022, a multi-national mpox outbreak was reported in several non-endemic countries. The only licensed treatment for mpox in the European Union is the orally available small molecule tecovirimat, which in O...
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Article
Open AccessDisseminated tuberculosis during TNF-α inhibitor therapy diagnosed by positron emission tomography and mini-laparoscopy
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Article
Therapie der Tuberkulose: Was gibt es Neues?
Noch nie waren so viele Menschen auf der Welt gleichzeitig an einer Tuberkulose erkrankt wie in der heutigen Zeit. Auch ist die Tuberkulose weiterhin die häufigste zum Tode führende bakterielle Infektionskrank...
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Article
Open AccessOrthopox simiae muscle abscess
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Article
Open AccessRespiratory muscle dysfunction in long-COVID patients
Symptoms often persistent for more than 4 weeks after COVID-19—now commonly referred to as ‘Long COVID’. Independent of initial disease severity or pathological pulmonary functions tests, fatigue, exertional i...
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Article
Open AccessDiagnosis of abdominal tuberculosis by mini-laparoscopy
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Erratum zu: Imitation eines Felty-Syndroms durch eine viszerale Leishmaniasis bei rheumatoider Arthritis unter Therapie mit Methotrexat und Etanercept
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Imitation eines Felty-Syndroms durch eine viszerale Leishmaniasis bei rheumatoider Arthritis unter Therapie mit Methotrexat und Etanercept
Die viszerale Leishmaniasis (VL) ist eine chronische Parasitose, die durch Erreger der Gattung Leishmania ausgelöst wird und zahlreiche Erkrankungen imitieren kann. Die Leitsymptome der VL (Splenomegalie, Panzyto...
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Article
Open AccessDisturbed lipid and amino acid metabolisms in COVID-19 patients
The Coronavirus disease 2019 (COVID-19) pandemic is overwhelming the healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to new biomarkers and therapeutic targets for monitor...
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Article
Open AccessWound infection with Vibrio harveyi following a traumatic leg amputation after a motorboat propeller injury in Mallorca, Spain: a case report and review of literature
Vibrio spp. are aquatic bacteria that are ubiquitous in warm estuarine and marine environments, of which 12 species are currently known to cause infections in humans. So far, only five human infections with V. ha...
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Article
Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center
To determine epidemiological, clinical and laboratory characteristics of leptospirosis, 24 consecutive patients diagnosed with the infection between 2011 and 2017 at the University Medical Center Hamburg-Eppen...
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Article
High proportion of HIV late presenters at an academic tertiary care center in northern Germany confirms the results of several cohorts in Germany: time to put better HIV screening efforts on the national agenda?
165 treatment-naive patients who first presented at the infectious disease clinic of the University Medical Center Hamburg-Eppendorf from 2009 to 2011 were retrospectively analyzed with emphasis on patients wi...
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Living Reference Work Entry In depth
Infektionen des zentralen Nervensystems
Infektionserkrankungen des zentralen Nervensystems (ZNS) werden von unterschiedlichen bakteriellen, viralen, parasitären Erregern und Pilzen hervorgerufen. Sowohl das Erregerspektrum als auch die Symptomatik i...
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Article
Open AccessSafety and efficacy of protease inhibitor based combination therapy in a single-center “real-life” cohort of 110 patients with chronic hepatitis C genotype 1 infection
The combination of boceprevir or telaprevir with peginterferon-alfa and ribavirin for the treatment of patients infected with HCV genotype 1 has led to significantly increased rates of sustained virological re...
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Article
PKCμ prevents CD95-mediated apoptosis and enhances proliferation in pancreatic tumour cells
Loss of growth control and a marked resistance to apoptosis are considered major mechanisms driving tumour progression. Protein kinases C (PKC) have been shown to be important in the regulation of proliferatio...
