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  1. Article

    Open Access

    Gentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis: a retrospective analysis

    Listeria monocytogenes causes severe bacterial infections with the highest mortality rate among foodborne pathogens in Europe. Combination treatment with ampicillin and gentamicin is recommended for invasive mani...

    Jan P. Sutter, Lorenz Kocheise, Jan Kempski, Martin Christner in Infection (2024)

  2. Article

    Open Access

    High burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022

    Bacterial pneumonia, a major cause of respiratory tract infections (RTI), can be challenging to diagnose and to treat adequately, especially when seasonal viral pathogens co-circulate. The aim of this study wa...

    Marlene Ettemeyer, Maria Florey, Konstantin Tanida, Johannes Jochum in Infection (2023)

  3. Article

    Open Access

    Tecovirimat for the treatment of severe Mpox in Germany

    In May 2022, a multi-national mpox outbreak was reported in several non-endemic countries. The only licensed treatment for mpox in the European Union is the orally available small molecule tecovirimat, which in O...

    Lennart Hermanussen, Thomas Theo Brehm, Timo Wolf, Christoph Boesecke in Infection (2023)

  4. Article

    Open Access

    Disseminated tuberculosis during TNF-α inhibitor therapy diagnosed by positron emission tomography and mini-laparoscopy

    Lennart Hermanussen, Thomas Theo Brehm, Stefan Schmiedel in Infection (2023)

  5. No Access

    Article

    Therapie der Tuberkulose: Was gibt es Neues?

    Noch nie waren so viele Menschen auf der Welt gleichzeitig an einer Tuberkulose erkrankt wie in der heutigen Zeit. Auch ist die Tuberkulose weiterhin die häufigste zum Tode führende bakterielle Infektionskrank...

    Thomas Theo Brehm, Niklas Köhler, Stefan Schmiedel, Elena Terhalle in Die Innere Medizin (2023)

  6. Article

    Open Access

    Orthopox simiae muscle abscess

    Thomas Theo Brehm, Lennart Hermanussen, Stefan Schmiedel in Infection (2023)

  7. Article

    Open Access

    Mini-laparoscopy as a diagnostic tool for abdominal tuberculosis: a retrospective series of 29 cases

    Abdominal tuberculosis (TB) is a “great mimic,” and diagnosis remains challenging even for experienced clinicians. While mini-laparoscopy has already been demonstrated to be an efficient diagnostic tool for a ...

    Thomas Theo Brehm, Natascha Ndzedzeka-Völz, Malte Wehmeyer in Surgical Endoscopy (2023)

  8. Article

    Open Access

    Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial

    Patients with cancer are at high risk of severe coronavirus disease 2019 (COVID-19), with high morbidity and mortality. Furthermore, impaired humoral response renders severe acute respiratory syndrome coronavi...

    Claudia M. Denkinger, Maike Janssen, Ulrike Schäkel, Julia Gall in Nature Cancer (2023)

  9. Article

    Open Access

    Respiratory muscle dysfunction in long-COVID patients

    Symptoms often persistent for more than 4 weeks after COVID-19—now commonly referred to as ‘Long COVID’. Independent of initial disease severity or pathological pulmonary functions tests, fatigue, exertional i...

    Jan K. Hennigs, Marie Huwe, Annette Hennigs, Tim Oqueka, Marcel Simon in Infection (2022)

  10. Article

    Open Access

    Diagnosis of abdominal tuberculosis by mini-laparoscopy

    Thomas Theo Brehm, Stefan Schmiedel, Ansgar W. Lohse in Infection (2022)

  11. Article

    Open Access

    Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome

    Vaccine development is essential for pandemic preparedness. We previously conducted a Phase 1 clinical trial of the vector vaccine candidate MVA-MERS-S against the Middle East respiratory syndrome coronavirus ...

    Anahita Fathi, Christine Dahlke, Verena Krähling, Alexandra Kupke in Nature Communications (2022)

  12. Article

    Erratum zu: Imitation eines Felty-Syndroms durch eine viszerale Leishmaniasis bei rheumatoider Arthritis unter Therapie mit Methotrexat und Etanercept

    Nikolas Ruffer, Nicola M. Tomas, Stefan Schmiedel in Zeitschrift für Rheumatologie (2022)

  13. No Access

    Article

    Imitation eines Felty-Syndroms durch eine viszerale Leishmaniasis bei rheumatoider Arthritis unter Therapie mit Methotrexat und Etanercept

    Die viszerale Leishmaniasis (VL) ist eine chronische Parasitose, die durch Erreger der Gattung Leishmania ausgelöst wird und zahlreiche Erkrankungen imitieren kann. Die Leitsymptome der VL (Splenomegalie, Panzyto...

    Nikolas Ruffer, Nicola M. Tomas, Stefan Schmiedel in Zeitschrift für Rheumatologie (2022)

  14. Article

    Open Access

    Disturbed lipid and amino acid metabolisms in COVID-19 patients

    The Coronavirus disease 2019 (COVID-19) pandemic is overwhelming the healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to new biomarkers and therapeutic targets for monitor...

    Mojgan Masoodi, Manuela Peschka, Stefan Schmiedel in Journal of Molecular Medicine (2022)

  15. Article

    Open Access

    Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza

    While several studies have described the clinical course of patients with coronavirus disease 2019 (COVID-19), direct comparisons with patients with seasonal influenza are scarce. We compared 166 patients with...

    Thomas Theo Brehm, Marc van der Meirschen, Annette Hennigs in Scientific Reports (2021)

  16. No Access

    Chapter

    Parasitäre Infektionen in der AVC – die Echinokokkose

    Die Echinokokkosen des Menschen sind parasitäre Infektionen mit meist primärem Leberbefall. Es existiert die weltweit verbreitete zystische Echinokokkose (Hundebandwurm) sowie die alveoläre Echinokokkose, ein ...

    Lutz Fischer, Jun Li, Stefan Schmiedel in Infektionen in der Allgemein- und Viszeral… (2021)

  17. No Access

    Chapter

    Enzephalitis

    Virale Infektionen des Nervensystems sind häufig ein neurologischer Notfall und differenzialdiagnostisch anspruchsvoll und können durch eine Vielzahl von Erregern ausgelöst werden. Die rasche Diagnose und ansc...

    Uta Meyding-Lamadé, Eva Maria Craemer, Martin Stangel in Neuroinfektiologie (2021)

  18. Article

    Open Access

    Wound infection with Vibrio harveyi following a traumatic leg amputation after a motorboat propeller injury in Mallorca, Spain: a case report and review of literature

    Vibrio spp. are aquatic bacteria that are ubiquitous in warm estuarine and marine environments, of which 12 species are currently known to cause infections in humans. So far, only five human infections with V. ha...

    Thomas Theo Brehm, Laura Berneking, Holger Rohde in BMC Infectious Diseases (2020)

  19. No Access

    Chapter

    Gastroenteritiden und Peritonitis

    Gastroenteritiden und Enterokolitiden sind Erkrankungen der Schleimhäute des Magen-Darm-Trakts, die durch Mikroorganismen oder deren Toxine verursacht werden. Sie führen klinisch zu Übelkeit, Erbrechen, Durchf...

    Christoph Lübbert, Stefan Schmiedel in Medizinische Mikrobiologie und Infektiologie (2020)

  20. Article

    Open Access

    Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)

    To evaluate clinical outcomes after either immediate or deferred initiation of antiretroviral therapy in HIV-1-infected patients, presenting late with pneumocystis pneumonia (PCP) or toxoplasma encephalitis (TE).

    Guido Schäfer, Christian Hoffmann, Keikawus Arasteh in AIDS Research and Therapy (2019)

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