19 Result(s)
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Article
Open AccessGentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis: a retrospective analysis
Listeria monocytogenes causes severe bacterial infections with the highest mortality rate among foodborne pathogens in Europe. Combination treatment with ampicillin and gentamicin is recommended for invasive mani...
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Article
Open AccessHigh burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022
Bacterial pneumonia, a major cause of respiratory tract infections (RTI), can be challenging to diagnose and to treat adequately, especially when seasonal viral pathogens co-circulate. The aim of this study wa...
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Article
Open AccessTecovirimat for the treatment of severe Mpox in Germany
In May 2022, a multi-national mpox outbreak was reported in several non-endemic countries. The only licensed treatment for mpox in the European Union is the orally available small molecule tecovirimat, which in O...
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Open AccessDisseminated tuberculosis during TNF-α inhibitor therapy diagnosed by positron emission tomography and mini-laparoscopy
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Article
Open AccessOrthopox simiae muscle abscess
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Article
Open AccessRespiratory muscle dysfunction in long-COVID patients
Symptoms often persistent for more than 4 weeks after COVID-19—now commonly referred to as ‘Long COVID’. Independent of initial disease severity or pathological pulmonary functions tests, fatigue, exertional i...
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Article
Open AccessDiagnosis of abdominal tuberculosis by mini-laparoscopy
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Chapter
Parasitäre Infektionen in der AVC – die Echinokokkose
Die Echinokokkosen des Menschen sind parasitäre Infektionen mit meist primärem Leberbefall. Es existiert die weltweit verbreitete zystische Echinokokkose (Hundebandwurm) sowie die alveoläre Echinokokkose, ein ...
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Chapter
Enzephalitis
Virale Infektionen des Nervensystems sind häufig ein neurologischer Notfall und differenzialdiagnostisch anspruchsvoll und können durch eine Vielzahl von Erregern ausgelöst werden. Die rasche Diagnose und ansc...
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Article
Open AccessWound infection with Vibrio harveyi following a traumatic leg amputation after a motorboat propeller injury in Mallorca, Spain: a case report and review of literature
Vibrio spp. are aquatic bacteria that are ubiquitous in warm estuarine and marine environments, of which 12 species are currently known to cause infections in humans. So far, only five human infections with V. ha...
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Article
Open AccessImmediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study)
To evaluate clinical outcomes after either immediate or deferred initiation of antiretroviral therapy in HIV-1-infected patients, presenting late with pneumocystis pneumonia (PCP) or toxoplasma encephalitis (TE).
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Article
Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center
To determine epidemiological, clinical and laboratory characteristics of leptospirosis, 24 consecutive patients diagnosed with the infection between 2011 and 2017 at the University Medical Center Hamburg-Eppen...
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Article
Open AccessScreening and contact precautions – A survey on infection control measures for multidrug-resistant bacteria in German university hospitals
To assess the scope of infection control measures for multidrug-resistant bacteria in high-risk settings, a survey among university hospitals was conducted. Fourteen professionals from 8 sites participated. Re...
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Article
High proportion of HIV late presenters at an academic tertiary care center in northern Germany confirms the results of several cohorts in Germany: time to put better HIV screening efforts on the national agenda?
165 treatment-naive patients who first presented at the infectious disease clinic of the University Medical Center Hamburg-Eppendorf from 2009 to 2011 were retrospectively analyzed with emphasis on patients wi...
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Article
Open AccessGerman cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients
Current German and European HIV guidelines recommend early evaluation of HCV treatment in all HIV/HCV co-infected patients. However, there are still considerable barriers to initiate HCV therapy in everyday cl...
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Article
Open AccessArtesunate versus quinine in the treatment of severe imported malaria: comparative analysis of adverse events focussing on delayed haemolysis
Severe malaria is a potentially life-threatening infectious disease. It has been conclusively shown that artesunate compared to quinine is superior in antiparasitic efficacy and in lowering mortality showing a...
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Article
Open AccessPost-treatment haemolysis in severe imported malaria after intravenous artesunate: case report of three patients with hyperparasitaemia
Parenteral artesunate has been shown to be a superior treatment option compared to parenteral quinine in adults and children with severe malaria. Little evidence, however, is available on long-term safety. Rec...
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Article
Open AccessReduced cardiac output in imported Plasmodium falciparum malaria
Volume substitution remains subject of controversy in the light of effusions and oedema potentially complicating this highly febrile disease. Understanding the role of myocardial and circulatory function appea...
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Article
Open AccessProcalcitonin serum levels in tertian malaria
Procalcitonin (PCT) is closely correlated with parasite burden and clinical outcome in falciparum malaria. The role of PCT in tertian malaria has not previously been investigated.
