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Open AccessCorrection: Network Meta-analysis of Ravulizumab and Alternative Interventions for the Treatment of Neuromyelitis Optica Spectrum Disorder
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Article
Open AccessNetwork Meta-analysis of Ravulizumab and Alternative Interventions for the Treatment of Neuromyelitis Optica Spectrum Disorder
Anti-aquaporin-4 antibody-positive (AQP4-Ab+) neuromyelitis optica spectrum disorder (NMOSD) is a complement-mediated autoimmune disease in which unpredictable and relapsing attacks on the central nervous syst...
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Article
Open AccessAuthor Correction: Gene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization
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Article
Open AccessGene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization
With increasing utilization of comprehensive genomic data to guide clinical care, anticipated to become the standard of care in many clinical settings, the practice of diagnostic medicine is undergoing a notab...
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Clinical Approach to Stiff Person Syndrome
Stiff person syndrome (SPS) was first described by Moersch and Woltman in 1956 at the Mayo Clinic in a series of 14 men, hence the original terminology of stiff man syndrome. Clinically, patients were described t...
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Article
Open AccessPathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica
Pathogenic autoantibodies associated with neuromyelitis optica (NMO) induce disease by targeting aquaporin-4 (AQP4) water channels enriched on astrocytic endfeet at blood–brain interfaces. AQP4 is also express...
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Article
NMDAR Encephalitis Following Herpes Simplex Virus Encephalitis
Herpes simplex virus encephalitis (HSVE) is often associated with significant morbidity and mortality, and despite appropriate treatment with antivirals, worsening of neurological symptoms or relapse occurs in...
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Article
Open AccessNeuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures
Anti-Hu and anti-Ri antibodies are paraneoplastic immunoglobulin (Ig)G autoantibodies which recognize cytoplasmic and nuclear antigens present in all neurons. Although both antibodies produce similar immunohis...