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  1. No Access

    Article

    Clinical and serological insights into paraneoplastic brachial amyotrophic diplegia

    Brachial amyotrophic diplegia (BAD) is typically linked to a neurodegenerative etiology such as amyotrophic lateral sclerosis (ALS). Clinical and serological characterizations of paraneoplastic neurologic synd...

    Haidara Kherbek, Christopher Y. Itoh, Catherine Daley in Journal of Neurology (2024)

  2. Article

    Open Access

    Clinical features and outcomes in primary nervous system histiocytic neoplasms

    Nabeela Nathoo, Joon H. Uhm, Alyx B. Porter, Julie Hammack in Blood Cancer Journal (2024)

  3. Article

    Open Access

    Correction: Network Meta-analysis of Ravulizumab and Alternative Interventions for the Treatment of Neuromyelitis Optica Spectrum Disorder

    Stacey L. Clardy, Sean J. Pittock, Orhan Aktas, ** Nakahara in Neurology and Therapy (2024)

  4. Article

    Open Access

    Network Meta-analysis of Ravulizumab and Alternative Interventions for the Treatment of Neuromyelitis Optica Spectrum Disorder

    Anti-aquaporin-4 antibody-positive (AQP4-Ab+) neuromyelitis optica spectrum disorder (NMOSD) is a complement-mediated autoimmune disease in which unpredictable and relapsing attacks on the central nervous syst...

    Stacey L. Clardy, Sean J. Pittock, Orhan Aktas, ** Nakahara in Neurology and Therapy (2024)

  5. No Access

    Article

    Frequency of demyelinating disease activity following immune checkpoint inhibitor cancer immunotherapy

    Shemonti Hasan, Onilia Zorio, B. Mark Keegan, Brian G. Weinshenker in Journal of Neurology (2023)

  6. Article

    Open Access

    Eculizumab for the treatment of glycine receptor antibody associated stiff-person syndrome

    Jennifer A. McCombe, Bryan T. Klassen, Eoin P. Flanagan in Journal of Neurology (2023)

  7. No Access

    Article

    Sleep disturbances associated with DPPX autoantibodies: a case series

    To describe a case series of patients with prominent sleep disturbances and their polysomnography findings in six patients with dipeptidyl-peptidase-like protein-6 (DPPX) autoimmunity syndrome.

    Avi Gadoth, Michelle F. Devine, Sean J. Pittock, Andrew McKeon in Journal of Neurology (2023)

  8. Article

    Open Access

    Author Correction: Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis

    Hadas Stiebel-Kalish, Kerstin Rubarth, Karny Shouchane-Blum in Scientific Reports (2023)

  9. Article

    Open Access

    Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis

    Optic neuritis (ON) is a frequent presentation at onset of multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). ...

    Hadas Stiebel-Kalish, Kerstin Rubarth, Karny Shouchane-Blum in Scientific Reports (2022)

  10. Article

    Open Access

    A Response to: Letter to the Editor Regarding “Network Meta-analysis of Food and Drug Administration-approved Treatment Options for Adults with Aquaporin-4 Immunoglobulin G-positive Neuromyelitis Optica Spectrum Disorder”

    Dean M. Wingerchuk, Ina Zhang, Adrian Kielhorn, Minying Royston in Neurology and Therapy (2022)

  11. Article

    Anti-complement Agents for Autoimmune Neurological Disease

    In recent years, there has been increasing recognition of the diversity of autoimmune neurological diseases affecting all levels of the nervous system. A growing understanding of disease pathogenesis has enabl...

    Jennifer A. McCombe, Sean J. Pittock in Neurotherapeutics (2022)

  12. Article

    Open Access

    Network Meta-analysis of Food and Drug Administration-approved Treatment Options for Adults with Aquaporin-4 Immunoglobulin G-positive Neuromyelitis Optica Spectrum Disorder

    Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease defined by attacks on the central nervous system that cause irreversible damage. Recent approval of NMOSD therapies warrants investigatio...

    Dean M. Wingerchuk, Ina Zhang, Adrian Kielhorn, Minying Royston in Neurology and Therapy (2022)

  13. No Access

    Article

    Hope for patients with neuromyelitis optica spectrum disorders — from mechanisms to trials

    Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of NMOSD is supported by the de...

    Sean J. Pittock, Anastasia Zekeridou, Brian G. Weinshenker in Nature Reviews Neurology (2021)

  14. No Access

    Article

    Use of diffusion-weighted imaging to distinguish seizure-related change from limbic encephalitis

    To determine whether diffusion-weighted imaging (DWI) can help differentiate peri-ictal signal abnormality from limbic encephalitis (LE) among patients with medial temporal lobe T2-hyperintensity.

    Adrian Budhram, Jeffrey W. Britton, Greta B. Liebo, Divyanshu Dubey in Journal of Neurology (2020)

  15. Article

    Open Access

    The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody

    We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG) antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort. We histopathologically analyzed 2 autopsie...

    Romana Höftberger, Yong Guo, Eoin P. Flanagan in Acta Neuropathologica (2020)

  16. No Access

    Chapter

    Paraneoplastic Neurologic Disease

    Paraneoplastic neurologic disease (PND) is characterized by an aberrant immune-mediated response against the nervous system in the context of an underlying malignancy. Certain malignancies are more notorious f...

    Nicholas L. Zalewski, Sean J. Pittock in Neurorheumatology (2019)

  17. Article

    Open Access

    GAD65 autoantibody characteristics in patients with co-occurring type 1 diabetes and epilepsy may help identify underlying epilepsy etiologies

    Autoantibodies against the smaller isoform of glutamate decarboxylase (GAD65Ab) reflect autoimmune etiologies in Type 1 diabetes (T1D) and several neurological disorders, including Stiff Person Syndrome (SPS)....

    Suvi Liimatainen, Jerome Honnorat, Sean J. Pittock in Orphanet Journal of Rare Diseases (2018)

  18. No Access

    Article

    MRI findings in glutamic acid decarboxylase associated autoimmune epilepsy

    Glutamic acid decarboxylase (GAD65) has been implicated in a number of autoimmune-associated neurologic syndromes, including autoimmune epilepsy. This study categorizes the spectrum of MRI findings in patients...

    Jason R. Fredriksen, Carrie M. Carr, Kelly K. Koeller, Jared T. Verdoorn in Neuroradiology (2018)

  19. No Access

    Article

    Breast cancer-related paraneoplastic neurologic disease

    Paraneoplastic neurologic disease (PND) is an aberrant immune-mediated response against the nervous system triggered by malignancy. Given the rarity, a paucity of data describing breast cancer-related PND (BC-...

    Brittany L. Murphy, Nicholas L. Zalewski in Breast Cancer Research and Treatment (2018)

  20. Article

    Open Access

    Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica

    Pathogenic autoantibodies associated with neuromyelitis optica (NMO) induce disease by targeting aquaporin-4 (AQP4) water channels enriched on astrocytic endfeet at blood–brain interfaces. AQP4 is also express...

    Yong Guo, Stephen D. Weigand, Bogdan F. Popescu, Vanda A. Lennon in Acta Neuropathologica (2017)

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