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  1. Article

    Open Access

    The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis

    Idiopathic pulmonary fibrosis (IPF) is a chronic, fatal, fibrotic, interstitial lung disease of unknown cause. Despite extensive studies, the underlying mechanisms of IPF development remain unknown. Here, we f...

    Soo Yeon Lee, Soo-Yeon Park, Seung-Hyun Lee in Experimental & Molecular Medicine (2023)

  2. No Access

    Chapter and Conference Paper

    Anti-inflammatory Effects of Galactose-Taurine Sodium Salt: A Taurine Derivate in Zebrafish In Vivo Model

    Taurine, the plentiful amino acids in mammalian cells exerts various biological activities including antioxidant and anti-inflammatory effects. Inflammation can cause several diseases such as cancer, heart dis...

    Eun A. Kim, WonWoo Lee, Ju Hyung Um, Nalae Kang, Sun Hee Cheong, Jae Young Oh in Taurine 10 (2017)

  3. No Access

    Chapter and Conference Paper

    Xylose-Taurine Reduced Suppresses the Inflammatory Responses in Lipopolysaccharide-Stimulated Raw264.7 Macrophages

    Here, the anti-inflammatory effect of Xylose-Taurine reduced (X-T-R), a taurine derivate was investigated in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. X-T-R reduced the generations of nitric oxide (...

    WonWoo Lee, Nalae Kang, Soo Yeon Park, Sun Hee Cheong, Kyung Ja Chang in Taurine 10 (2017)

  4. No Access

    Chapter and Conference Paper

    Anti-inflammatory Effects of Galactose-Taurine Sodium Salt in LPS-Activated RAW 264.7 Cells

    In this study, we synthesized Galactose-Taurine sodium salt (G-T) as a functional food ingredient to enhance biological activities of taurine. Also, anti-inflammatory effects of G-T were investigated in lipopo...

    Nalae Kang, Kyung Ja Chang, Soo Yeon Park, Ju Hyung Um, Eui Jeong Han in Taurine 10 (2017)

  5. No Access

    Chapter and Conference Paper

    Protective Effects of Xylose-Taurine Reduced against Damages Caused by Oxidative Stress in Zebrafish Embryos In Vivo Model

    The zebrafish (Danio rerio) is useful and convenient vertebrate models in various studies in human disease and drug discovery. In this present study, we first evaluated whether Xylose-Taurine reduced (X-T-R), a t...

    WonWoo Lee, Eun-A. Kim, Ju Hyung Um, Nalae Kang, Jae Young Oh, Soo Yeon Park in Taurine 10 (2017)

  6. No Access

    Chapter and Conference Paper

    Hepatoprotective Effects of Xylose-Taurine Reduced Against Hydrogen Peroxide-Induced Oxidative Stress in Cultured Hepatocytes

    In this study, Xylose-Taurine reduced (X-T-R) was synthesized to enhance biological activities. Hence, we investigated the hepatoprotective effects of X-T-R against H2O2-induced hepatocyte damage and apoptosis. T...

    Soo Yeon Park, Chang-Bum Ahn, Kyung Ja Chang, Sung Hoon Kim, WonWoo Lee in Taurine 10 (2017)

  7. No Access

    Chapter and Conference Paper

    Radio-Protective Effects of Octopus ocellatus Meat Consisted of a Plentiful Taurine Against Damages Caused by Gamma Ray Irradiation

    Gamma ray irradiation causes immune suppressive responses by inducing oxidative stress such as reduction of cell viability and damages in immune cells. In this present study, we investigated whether Octopus ocell...

    WonWoo Lee, Eun A. Kim, Ju Hyung Um, Nalae Kang, Eui Jeong Han, Jae Young Oh in Taurine 10 (2017)

  8. No Access

    Chapter and Conference Paper

    Protective Effects of An Enzymatic Hydrolysate from Octopus ocellatus Meat against Hydrogen Peroxide-Induced Oxidative Stress in Chang Liver Cells and Zebrafish Embryo

    Octopus ocellatus, a marine cephalopod distributed in the coast of South Korea, China, Japan and tropical sea, contains high amounts of taurine. In this study, an enzymatic hydrolysate obtained from O. ocellatus

    Ju Hyung Um, Eun-A Kim, WonWoo Lee, Nalae Kang, Eui Jeong Han, Jae Young Oh in Taurine 10 (2017)

  9. No Access

    Chapter and Conference Paper

    Protective Effects of An Water Extracts Prepared from Loliolus beka Gray Meat Against H2O2-Induced Oxidative Stress in Chang Liver Cells and Zebrafish Embryo Model

    In this study, we first evaluated protective effects of Loliolus beka in a human liver cell line and zebrafish embryo model with its anti-oxidant activity. First, we prepared the water extract from L. beka meat (...

    Eui Jeong Han, Ju Hyung Um, Eun A. Kim, WonWoo Lee, Nalae Kang, Jae Young Oh in Taurine 10 (2017)