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    Protocol

    Software Supporting a Workflow of Quantitative Dynamic Flux Maps Estimation in Central Metabolism from SIRM Experimental Data

    Stable isotope-resolved metabolomics (SIRM), based on the analysis of biological samples from living cells incubated with artificial isotope enriched substrates, enables map** the rates of biochemical reacti...

    Vitaly A. Selivanov, Silvia Marin in Metabolic Flux Analysis in Eukaryotic Cells (2020)

  2. Article

    Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

    Reza M. Salek, Steffen Neumann, Daniel Schober, Jan Hummel, Kenny Billiau in Metabolomics (2015)

  3. Article

    Open Access

    COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

    Metabolomics has become a crucial phenoty** technique in a range of research fields including medicine, the life sciences, biotechnology and the environmental sciences. This necessitates the transfer of exp...

    Reza M. Salek, Steffen Neumann, Daniel Schober, Jan Hummel, Kenny Billiau in Metabolomics (2015)

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    Article

    Exploring the Feasibility of the Sec Route to Secrete Proteins Using the Tat Route in Streptomyces lividans

    Streptomyces lividans uses mainly two pathways to target secretory proteins to the cytoplasmic membrane. The major pathway (Sec pathway) transports pre-proteins using the signal recogniti...

    Sonia Gullón, Rebeca L. Vicente, José R. Valverde, Silvia Marín in Molecular Biotechnology (2015)

  5. No Access

    Article

    Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle

    Cyclin-dependent kinases CDK4 and CDK6 are essential for the control of the cell cycle through the G1 phase. Aberrant expression of CDK4 and CDK6 is a hallmark of cancer, which would suggest that CDK4 and CDK6 ar...

    Miriam Zanuy, Antonio Ramos-Montoya, Oscar Villacañas, Nuria Canela in Metabolomics (2012)

  6. No Access

    Article

    Metabolic profile and quantification of deoxyribose synthesis pathways in HepG2 cells

    Traditional tracer studies of cell proliferation fail to distinguish between label enrichment due to increased DNA repair versus DNA replication. We used the emerging stable (non-radiating) isotope-based dynam...

    Josep J. Centelles, Antonio Ramos-Montoya, Shu Lim, Sara Bassilian in Metabolomics (2007)