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Software Supporting a Workflow of Quantitative Dynamic Flux Maps Estimation in Central Metabolism from SIRM Experimental Data
Stable isotope-resolved metabolomics (SIRM), based on the analysis of biological samples from living cells incubated with artificial isotope enriched substrates, enables map** the rates of biochemical reacti...
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Article
Erratum to: COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
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Article
Open AccessCOordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
Metabolomics has become a crucial phenoty** technique in a range of research fields including medicine, the life sciences, biotechnology and the environmental sciences. This necessitates the transfer of exp...
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Article
Exploring the Feasibility of the Sec Route to Secrete Proteins Using the Tat Route in Streptomyces lividans
Streptomyces lividans uses mainly two pathways to target secretory proteins to the cytoplasmic membrane. The major pathway (Sec pathway) transports pre-proteins using the signal recogniti...
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Article
Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle
Cyclin-dependent kinases CDK4 and CDK6 are essential for the control of the cell cycle through the G1 phase. Aberrant expression of CDK4 and CDK6 is a hallmark of cancer, which would suggest that CDK4 and CDK6 ar...
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Metabolic profile and quantification of deoxyribose synthesis pathways in HepG2 cells
Traditional tracer studies of cell proliferation fail to distinguish between label enrichment due to increased DNA repair versus DNA replication. We used the emerging stable (non-radiating) isotope-based dynam...