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  1. Article

    Open Access

    P4-ATPase subunit Cdc50 plays a role in yeast budding and cell wall integrity in Candida glabrata

    As highly-conserved types of lipid flippases among fungi, P4-ATPases play a significant role in various cellular processes. Cdc50 acts as the regulatory subunit of flippases, forming heterodimers with Drs2 to ...

    Ke-Zhi Chen, Lu-Ling Wang, **-Yan Liu, Jun-Tao Zhao, Si-Jia Huang in BMC Microbiology (2023)

  2. No Access

    Article

    Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy

    Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in the developed world. Podocyte injury is a critical cellular event involved in the progression of DN. Our previous studies demonstrat...

    Si Jia Huang, Yang Zhang, Gui Hua Wang, Jian Lu in International Urology and Nephrology (2023)

  3. No Access

    Article

    Gut microbiota dysbiosis-induced activation of the intrarenal renin–angiotensin system is involved in kidney injuries in rat diabetic nephropathy

    Some studies have shown that gut microbiota along with its metabolites is closely associated with diabetic mellitus (DM). In this study we explored the relationship between gut microbiota and kidney injuries o...

    Chen-chen Lu, Ze-bo Hu, Ru Wang, Ze-hui Hong, Jian Lu in Acta Pharmacologica Sinica (2020)

  4. Article

    Open Access

    Urinary podocyte microparticles are associated with disease activity and renal injury in systemic lupus erythematosus

    New non-invasive biomarkers are demanded to identify renal damage in various autoimmune-associated kidney diseases. Glomerular podocyte damage mediated by systemic lupus erythematosus (SLE) plays an important ...

    Jian Lu, Ze Bo Hu, Pei Pei Chen, Chen Chen Lu, Jia **u Zhang, Xue Qi Li in BMC Nephrology (2019)

  5. No Access

    Article

    PROSE: Proactive, Selective CDN Participation for P2P Streaming

    Many production peer-to-peer (P2P) streaming systems use content delivery networks (CDN) to protect the user’s quality of experiences. Thus, how to efficiently utilize the capacity of CDN (e.g., which peers re...

    Zhi-Hui Lv, Li-Jiang Chen, Jie Wu, Da Deng in Journal of Computer Science and Technology (2013)