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  1. No Access

    Chapter

    Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis

    Circulating tumor cells offer an unprecedented window into the metastatic cascade, and to some extent can be considered as intermediates in the process of metastasis. They exhibit dynamic oscillations in epith...

    Risa Burr, Christine Gilles… in Circulating Tumor Cells in Breast Cancer M… (2020)

  2. Article

    Open Access

    Bevacizumab terminates homeobox B9-induced tumor proliferation by silencing microenvironmental communication

    Homeobox B9 (HOXB9), a transcriptional factor, regulates developmental processes and tumor progression and has recently been recognized as one of important transcriptional factors related to angiogenesis. This...

    Yoshinori Hoshino, Tetsu Hayashida, Akira Hirata, Hidena Takahashi… in Molecular Cancer (2014)

    Download PDF (2014 KB) View Article

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    Article

    The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour

    Chromosomal translocations resulting in chimaeric transcription factors underlie specific malignancies, but few authentic target genes regulated by these fusion proteins have been identified. Desmoplastic smal...

    Sean Bong Lee, Kathryn Ann Kolquist, Kim Nichols, Christoph Englert… in Nature Genetics (1997)

  4. No Access

    Article

    The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesothelioma

    The tumour suppressor gene WT1 encodes a transcription factor expressed in tissues of the genito–urinary system. Inactivation of this gene is associated with the development of Wilms tumour a pediatric kidney ...

    Seon Park, Martin Schalling, Amy Bernard, Shyamala Maheswaran… in Nature Genetics (1993)