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Article
ImmunoPET imaging of Trop2 expression in solid tumors with nanobody tracers
The high expression of the transmembrane glycoprotein trophoblast cell-surface antigen 2 (Trop2) was strongly associated with the progression of solid tumors, including pancreatic and gastric cancers. Our stud...
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Article
PET imaging of tumor vascular normalization in hepatocellular carcinoma
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Article
PSMA-targeted theranostics of solid tumors: applications beyond prostate cancers
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Article
GPC3-targeted immunoPET imaging of hepatocellular carcinomas
Early detection of hepatocellular carcinoma (HCC) remains a clinical challenge. Glypican 3 (GPC3) is a proteoglycan highly specific for HCC and is a potential diagnostic and therapeutic target for HCC. This wo...
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Article
ImmunoPET imaging of multiple myeloma with [68Ga]Ga-NOTA-Nb1053
Multiple myeloma (MM) remains incurable and its diagnosis relies heavily on bone marrow aspiration and biopsy. CD38 is a glycoprotein highly specific for MM. Antibody therapeutics (e.g., daratumumab) targeting...
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Article
Open AccessMet is involved in TIGAR-regulated metastasis of non-small-cell lung cancer
TIGAR is a p53 target gene that is known to protect cells from ROS-induced apoptosis by promoting the pentose phosphate pathway. The role of TIGAR in tumor cell invasion and metastasis remains elusive. Here we...
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Article
Body mass index and mortality in patients on maintenance hemodialysis: a meta-analysis
In patients undergoing maintenance hemodialysis (MHD), increasing numbers of studies have reported a reduced mortality in patients with an increased body mass index (BMI). This article provides a meta-analysis...