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Article
How does industrial transition drive low-carbon transition? Evidence from China’s resource-based cities
With the proposal of dual-carbon targets, the low-carbon transition of resource-based cities (RBCs) has become an urgent task. Industrial transition is an essential method of ensuring energy supplies and achie...
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Article
Open AccessDNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors
The development of SARS-CoV-2 main protease (Mpro) inhibitors for the treatment of COVID-19 has mostly benefitted from X-ray structures and preexisting knowledge of inhibitors; however, an efficient method to gen...
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Article
Structure, nitridation efficiency and magnetic properties of SmFe powders and its nitrides
The effect of annealing temperature (T A) at 600–900 °C on structure and magnetic properties of the melt-spun Sm8.6Fe85.9Co4.3Zr1.2 alloys and its nitrides was investigated. Results show that the ...
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Article
Open AccessCa2+ efflux facilitated by co-transport of inorganic phosphate anion in the H+/Ca2+ antiporter YfkE
Ca2+ is an important signaling messenger. In microorganisms, fungi, and plants, H+/Ca2+ antiporters (CAX) are known to play key roles in the homeostasis of intracellular Ca2+ by catalyzing its efflux across the c...
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Article
Hard magnetic properties of melt-spun nanocomposite Y16Fe78B6 ribbons
Melt-spun Y16Fe78B6 ribbons were prepared by the melt-spinning technique with pure elements Y, Fe and Fe–B alloy in argon. The ribbons are mainly composed of Y2Fe14B, YFe2 and α-Fe phases. Amorphous phase appears...
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Article
Open AccessAn active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M β-lactamase drug-resistance enzymes
β-lactamases inactivate β-lactam antibiotics leading to drug resistance. Consequently, inhibitors of β-lactamases can combat this resistance, and the β-lactamase inhibitory protein (BLIP) is a naturally occurr...
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Article
Experimental Study on Evolution of Fracture Network and Permeability Characteristics of Bituminous Coal Under Repeated Mining Effect
In a group of deep coal seams, mining of upper multilayers generates cyclic loading–unloading stresses in bottom layers, improving their permeability and enhancing coalbed methane gas drainage. In this study, ...
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Article
Open AccessIntegrated redox-active reagents for photoinduced regio- and stereoselective fluorocarboborylation
Vinylboronates and alkylboronates are key components in variegated transformations in all facets of chemical science. The synthesis of vinylboronates and alkylboronates suffers from step-tedious and poor stere...
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Article
Structure and magnetic properties of TbCu7-type melt-spun Sm–Fe–B alloys
The melt-spun SmFe12Bx (x = 0, 0.50, 0.75, 1.00, 1.25 and 1.50) ribbons were prepared at 40 m·s−1, and their structure and magnetic properties were studied by powder X-ray diffraction (XRD), vibrating sample magn...
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Article
Open AccessHigh resolution magnetic resonance imaging in pathogenesis diagnosis of single lenticulostriate infarction with nonstenotic middle cerebral artery, a retrospective study
It is usually difficult to identify stroke pathogenesis for single lenticulostriate infarction with nonstenotic middle cerebral artery (MCA). Our aim is to differentiate the two pathogeneses, non-branch athero...
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Protocol
Biochemical Reconstitution and Characterization of Multicomponent Drug Efflux Transporters
Efflux pumps are the major determinants in bacterial multidrug resistance. In Gram-negative bacteria, efflux transporters are organized as macromolecular tripartite machineries that span the two-membrane cell ...
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Article
Effects of changing climate and cultivar on the phenology and yield of winter wheat in the North China Plain
Understanding how changing climate and cultivars influence crop phenology and potential yield is essential for crop adaptation to future climate change. In this study, crop and daily weather data collected fro...
