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Article
Sensing and guiding cell-state transitions by using genetically encoded endoribonuclease-mediated microRNA sensors
Precisely sensing and guiding cell-state transitions via the conditional genetic activation of appropriate differentiation factors is challenging. Here we show that desired cell-state transitions can be guided...
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Article
Microstructure-Superplastic Properties Relationship and Deformation Mechanism in a Novel Dual-Phase Medium Mn Steel: The Effect of Microstructure Anisotropy and Texture
In this paper, the tensile properties, texture evolution, and deformation anisotropy of a cold-rolled Fe−0.3C–6.86Mn–3.5Al steel during superplastic deformation at 650 °C–750 °C and 0.25 × 10−3 s−1− 4 × 10−3 s−1 ...
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Article
Adaptive phase-field total Lagrangian material point method for evaluating dynamic fracture of soft material
An adaptive phase-field total Lagrangian material point method (APTLMPM) is proposed in this paper for effectively simulating the dynamic fracture of two-dimensional soft materials with finite deformation. In ...
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Article
Frequency spectrum prediction model of broaching process using theoretical cutting force time history
The amplitude of tooth passing frequency in frequency spectrum is an important indicator to judge machining quality and tool wear. In comparison to the amplitude of tooth passing frequency in acceleration spec...
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Article
Occurrence of microplastics in natural and farmland soil in the Qilian Mountains of the Northern Tibetan Plateau
Microplastics (MPs) become ubiquitous in soil and are an environmental and public health concern worldwide. However, the status of MPs in natural and farmland soils in remote areas remains poorly understood. I...
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Article
Van der Waals epitaxy of type-II band alignment CsPbI3/TMDC heterostructure for optoelectronic applications
Van der Waals epitaxy allows heterostructure formation without considering the lattice match requirement, thus is a promising method to form 2D/2D and 2D/3D heterojunction. Considering the unique optical prope...
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Article
Calycosin promotes axon growth by inhibiting PTPRS and alleviates spinal cord injury
Our former studies have identified the alleviating effect of Calycosin (CA) on spinal cord injury (SCI). In this study, our purpose is to explore the influence of CA on SCI from the perspective of promoting ax...
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Article
UTE-CrackNet: transformer-guided and edge feature extraction U-shaped road crack image segmentation
Cracks in the road surface can cause significant harm. Road crack detection, segmentation, and immediate repair can help reduce the occurrence of risks. Some methods based on convolutional neural networks stil...
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Article
Dosimetric evaluation and treatment planning considerations for GammaTile permanent brain implants – a pilot, institutional experience
GammaTile® (GT) is a brachytherapy platform that received Federal Drug Administration (FDA) approval as brain tumor therapy in late 2018. Here, we reviewed our institutional experience with GT as treatment for...
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Article
Genome-wide identification of the SAUR gene family and screening for SmSAURs involved in root development in Salvia miltiorrhiza
SmSAUR4, SmSAUR18, SmSAUR28, SmSAUR37, and SmSAUR38 were probably involved in the auxin-mediated root development in Salvia miltiorrhiza.
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Article
Open AccessModeling of distortional hardening including plane strain tension and pure shear for a TWIP steel
This paper focuses on calibrating and modeling of distortional hardening behaviours in twinning induced plasticity steels. True stress-strain curves for uniaxial tension, plane strain tension, and pure shear s...
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Article
Open AccessDesign and experiment of impeller seed guide device for rice internal suction hole direct seeding device
Multi-grain hole-forming sowing and uniform hole spacing are important agronomic requirements for precise hole-direct seeding of rice.This paper designs a kind of impeller type seed guiding device. The main st...
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Article
Open AccessGasdermin E benefits CD8+T cell mediated anti-immunity through mitochondrial damage to activate cGAS-STING-interferonβ axis in colorectal cancer
Pyroptosis belongs to a unique type of programmed cell death among which GSDME is reported to exert anti-tumor immunity. However, the underlying mechanisms of how to boost tumor-infiltrating lymphocytes and wh...
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Article
Experimental Evaluation of Slope Fissure Networks Under the Action of Multiseam Mining in Mountainous Areas
The collapse structure of overlying rock in multiseam mining exhibits dynamic changes, significant degrees of damage, and wide-ranging effects. Concurrently influenced by the topography and geomorphology, over...
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Article
Effect of Shot Peening Duration on Microstructure and Mechanical Properties of GH4169 Alloy Prepared by 3D Printing
This study explores the influence of different shot peening (SP) durations on the microstructure and mechanical properties of 3D printed GH4169 alloy. This investigation examines the changes of microstructure ...
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Article
Author Correction: Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos
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Article
Author Correction: Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing
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Article
Magnetic-Controlled Short Process Preparation Technique for Phosphor Bronze Based on Structure Refinement
The conventional preparation process for Phosphor bronze typically involves high-temperature long-duration solid solution treatment to address the issue of decreased workability caused by the precipitation of ...
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Article
An image compression-then-encryption algorithm using piecewise asymptotic deterministic random measurement matrix
A digital Image Compression Encryption Method (ICEM) is proposed in this work by using the Compressed Sensing (CS), two-dimensional Logistic-adjusted-Sine map, the piecewise asymptotic deterministic system, dy...
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Article
Oral delivery of ferroptosis inducers for effective treatment of hepatic fibrosis
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM), which is primarily produced by activated hepatic stellate cells (HSCs). However, effective therapies for hepatic fib...
