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  1. Article

    Open Access

    Understanding how junction resistances impact the conduction mechanism in nano-networks

    Networks of nanowires, nanotubes, and nanosheets are important for many applications in printed electronics. However, the network conductivity and mobility are usually limited by the resistance between the par...

    Cian Gabbett, Adam G. Kelly, Emmet Coleman, Luke Doolan in Nature Communications (2024)

  2. Article

    Open Access

    Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome

    Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that causes tuberculosis (TB), an infectious disease that is responsible for major health and economic costs worldwide1. Mtb encounters diverse environment...

    **angwu Ju, Shuqi Li, Ruby Froom, Ling Wang, Mirjana Lilic, Madeleine Delbeau in Nature (2024)

  3. Article

    Open Access

    Quantitative analysis of printed nanostructured networks using high-resolution 3D FIB-SEM nanotomography

    Networks of solution-processed nanomaterials are becoming increasingly important across applications in electronics, sensing and energy storage/generation. Although the physical properties of these devices are...

    Cian Gabbett, Luke Doolan, Kevin Synnatschke, Laura Gambini in Nature Communications (2024)

  4. Article

    Open Access

    Smc5/6’s multifaceted DNA binding capacities stabilize branched DNA structures

    Smc5/6 is an evolutionarily conserved SMC complex with roles in DNA replication and repair, as well as in viral DNA restriction. Understanding its multiple functions has been hampered by a lack of mechanistic ...

    Jeremy T-H. Chang, Shibai Li, Emily C. Beckwitt, Thane Than in Nature Communications (2022)

  5. Article

    Open Access

    Nucleosome-directed replication origin licensing independent of a consensus DNA sequence

    The numerous enzymes and cofactors involved in eukaryotic DNA replication are conserved from yeast to human, and the budding yeast Saccharomyces cerevisiae (S.c.) has been a useful model organism for these studie...

    Sai Li, Michael R. Wasserman, Olga Yurieva, Lu Bai in Nature Communications (2022)

  6. Article

    Open Access

    Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA

    Biomolecular condensation constitutes an emerging mechanism for transcriptional regulation. Recent studies suggest that the co-condensation between transcription factors (TFs) and DNA can generate mechanical f...

    Tuan Nguyen, Sai Li, Jeremy T-H Chang, John W. Watters, Htet Ng in Nature Communications (2022)

  7. Article

    Open Access

    A gland-sparing, intraoral sialolithotomy approach for hilar and intraparenchymal multiple stones in the submandibular gland

    Multiple intraglandular sialolithiasis for stones deep in the glandular parenchyma may require submandibulectomies, especially if sialendoscopic facilities are unavailable. We describe a gland-sparing intraora...

    Huan Shi, Jun Zhao, Eugene Poh Hze-Khoong, Shixin Liu, Xuelai Yin in Scientific Reports (2020)

  8. Article

    Open Access

    Reversible histone glycation is associated with disease-related changes in chromatin architecture

    Cellular proteins continuously undergo non-enzymatic covalent modifications (NECMs) that accumulate under normal physiological conditions and are stimulated by changes in the cellular microenvironment. Glycati...

    Qingfei Zheng, Nathaniel D. Omans, Rachel Leicher in Nature Communications (2019)