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Chapter
Concept of the Original Okabayashi’s Radical Hysterectomy
This surgery is designed for the treatment of invasive cervical cancer. The principle is the removal of the whole uterus with enough length of vaginal cuff dissecting the most distal portion of the uterine sup...
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Chapter
Correction to: Precise Neurovascular Anatomy for Radical Hysterectomy
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Chapter
Brief History of Surgical Treatment for Cervical Cancer
Cervical cancer that was visible from the vagina enabled the vaginal resection of the lesion in the prolapsed uterus. The amputation of the cervix of the prolapsed uterus for the surgical treatment of cervical...
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Chapter
Novel Points of Okabayashi’s Radical Hysterectomy
In the tissue of the paracervix, Okabayashi found a loose connective tissue space. The space is named as Okabayashi’s paravaginal space (Figure 5.1a, b). By insinuation of scissors into the space, the paracerv...
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Chapter
What Is Nerve-Sparing Radical Hysterectomy?
Since Wertheim introduced radical hysterectomy in 1911 [1], his method became the standard procedure for the surgical treatment of cervical cancer in Western Countries. However, in Japan, Takayama and Okabayas...
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Protocol
Chromatin Pull-Down Methodology Based on DNA Triple Helix Formation
Identification of the protein complexes associated with defined DNA sequence elements is essential to understand the numerous transactions in which DNA is involved, such as replication, repair, transcription, ...
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Chapter
Classification of Radical Hysterectomy
In Western countries, since Meigs’ publication on radical hysterectomy in 1954 [1], radical hysterectomy was revived as the standard treatment for early invasive cervical cancer. The surgical technique of Meig...
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Chapter
Atlas of the Original Okabayashi’s Transabdominal Radical Hysterectomy
The abdomen is opened by a midline incision which should be made a sufficient length to secure free exposure of the operative field. (This usually extends from the symphysis to above the umbilicus.)
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Book
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Chapter
Step-by-Step Radical Hysterectomy with Pelvic Lymphadenectomy (Without Nerve-Sparing)
Long Kocher forceps are placed close to the bilateral uterine body including the round ovarian ligaments as well as the fallopian tubes. The Kocher forceps are tied by a ribbon to use as a uterine retractor.
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Chapter
Step-by-Step Nerve-Sparing Radical Hysterectomy with Pelvic Lymphadenectomy
However, each surgical procedure until the division of the deep uterine vein in the cardinal ligament is the same as that of the step-by-step radical hysterectomy without nerve-sparing radical hysterectomy as ...
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Article
Open AccessChronological Switch from Translesion Synthesis to Homology-Dependent Gap Repair In Vivo
Cells are constantly exposed to endogenous and exogenous chemical and physical agents that damage their genome by forming DNA lesions. These lesions interfere with the normal functions of DNA such as transcrip...
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Article
Open AccessVersatile and efficient chromatin pull-down methodology based on DNA triple helix formation
The goal of present paper is to develop a reliable DNA-based method for isolation of protein complexes bound to DNA (Isolation of DNA Associated Proteins: IDAP). We describe a robust and versatile procedure to pu...
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Article
Surgical and systemic management of endometrial cancer: an international survey
To ascertain the spectrum of clinical management of endometrial carcinoma (EC) the largest international survey was conducted to evaluate and identify differences worldwide.
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Article
Expression of p53 and p21WAF-1, apoptosis, and proliferation of smooth muscle cells in normal myometrium during the menstrual cycle: implication of DNA damage and repair for leiomyoma development
Uterine leiomyoma is the most common tumor in the female genital tract, although its pathogenesis remains unclear. Molecular analyses have demonstrated that each leiomyoma nodule is monoclonal and harbors vari...
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Article
Clinical value of FDG-PET for preoperative evaluation of endometrial cancer
Whole body positron emission tomography (PET) with F-18 fluorodeoxyglucose (FDG) has been widely used in various malignancies, but the clinical value of FDG-PET for endometrial cancer has not been fully invest...
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Article
Thioredoxin Binding Protein-2 Inhibits Excessive Fetal Hypoglycemia During Maternal Starvation by Suppressing Insulin Secretion in Mice
Glucose is a major fuel for fetal development. Fetal blood glucose level is mainly dependent on maternal blood glucose concentration, though it is also regulated by fetal insulin level. Thioredoxin binding pro...
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Article
Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis
To investigate the clinical significance of the expression of the NKG2D ligands MICA/B and ULBP2 in ovarian cancer.
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Article
Cine MR imaging of uterine peristalsis in patients with endometriosis
Endometriosis is one of the most important causes of infertility; however the precise mechanism by which it affects female fertility is unclear. The objective of this study was to study the functional aspects ...
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Article
MR features of physiologic and benign conditions of the ovary
In reproductive women, various physiologic conditions can cause morphologic changes of the ovary, resembling pathologic conditions. Benign ovarian diseases can also simulate malignancies. Magnetic resonance im...
