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  1. Article

    Open Access

    Comparative transcriptome analysis reveals ectopic delta-5 and delta-6 desaturases enhance protective gene expression upon Vibrio vulnificus challenge in Tilapia (Oreochromis niloticus)

    Tilapia (Oreochromis niloticus) cultures are frequently infected by Vibrio vulnificus, causing major economic losses to production units. Previously, tilapia expressing recombinant delta-5 desaturase and delta-6 ...

    Pin-Yang Tu, Shin-Jie Huang, Venugopal Rajanbabu, Jen-Leih Wu, Jyh-Yih Chen in BMC Genomics (2021)

  2. Article

    Open Access

    Transgenic expression of omega-3 PUFA synthesis genes improves zebrafish survival during Vibrio vulnificus infection

    Highly desaturated n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are synthesized by desaturases and elongase. They exert hepatoprotective effects ...

    Chih-Lun Cheng, Shin-Jie Huang, Chih-Lu Wu, Hong-Yi Gong in Journal of Biomedical Science (2015)

  3. Article

    Open Access

    Transcriptome analysis of the effect of Vibrio alginolyticus infection on the innate immunity-related complement pathway in Epinephelus coioides

    Orange-spotted grouper (Epinephelus coioides) with protogynous hermaphroditic features are one of the most economically important aquaculture species in Taiwan. However, larvae stage grouper are susceptible to in...

    Yi-Da Wang, Shin-Jie Huang, Hong-Nong Chou, Wen-Liang Liao, Hong-Yi Gong in BMC Genomics (2014)