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Article
Open AccessTransgenic expression of omega-3 PUFA synthesis genes improves zebrafish survival during Vibrio vulnificus infection
Highly desaturated n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are synthesized by desaturases and elongase. They exert hepatoprotective effects ...
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Transgenic Technology in Marine Organisms
Marine organisms into which a foreign gene or non-coding deoxyribonucleic acid (DNA) fragment is artificially introduced and stably integrated in their genomes are termed transgenic marine organisms. Since the fi...
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Article
Open AccessTranscriptome analysis of the effect of Vibrio alginolyticus infection on the innate immunity-related complement pathway in Epinephelus coioides
Orange-spotted grouper (Epinephelus coioides) with protogynous hermaphroditic features are one of the most economically important aquaculture species in Taiwan. However, larvae stage grouper are susceptible to in...
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Article
Open AccessProgranulin regulates zebrafish muscle growth and regeneration through maintaining the pool of myogenic progenitor cells
Myogenic progenitor cell (MPC) is responsible for postembryonic muscle growth and regeneration. Progranulin (PGRN) is a pluripotent growth factor that is correlated with neuromuscular disease, which is charact...
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Article
Zebrafish eggs used as bioreactors for the production of bioactive tilapia insulin-like growth factors
Multiple advantages-including the short generation time, large numbers of fertilized eggs, low cost of cultivation and easy maintenance favor the use of fish as bioreactors for the production of pharmaceutical...
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Article
Nitroreductase-mediated Gonadal Dysgenesis for Infertility Control of Genetically Modified Zebrafish
Genetically modified (GM) fish with desirable features such as rapid growth, disease resistance, and cold tolerance, among other traits, have been established in aquaculture. However, commercially available GM...
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Article
Response to a Letter to the Editor from Rodgers regarding “Overexpression of Myostatin2 in zebrafish reduces the expression of dystrophin associated protein complex (DAPC) which leads to muscle dystrophy”
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Article
Overexpression of Myostatin2 in zebrafish reduces the expression of dystrophin associated protein complex (DAPC) which leads to muscle dystrophy
Myostatin, a member of the TGF-β superfamily, is a potent negative regulator of skeletal muscle and growth. Previously, we reported Mstn1 from zebrafish and studied its influence on muscle development. In this...
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Article
Isolation and characterization of the zebrafish Danio rerio insulin-like growth factor binding protein-3 promoter region
Insulin-like growth factor binding protein-3 (IGFBP-3) is expressed in many different cell types and has a regulatory function in the insulin-like growth factor (IGF) system. To further understand the molecula...
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Article
Thioacetamide induced liver damage in zebrafish embryo as a disease model for steatohepatitis
Steatohepatitis has recently been increasing as a cofactor influencing the progression of fibrosis, cirrhosis, adenoma and carcinoma in liver; however, the mechanisms by which it contributes to liver injury re...
