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Article
Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel
Site-1 sodium channel blockers (S1SCBs) act as potent local anaesthetics, but they can cause severe systemic toxicity. Delivery systems can be used to reduce the toxicity, but the hydrophilicity of S1SCBs make...
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Article
Open AccessParalytic shellfish poisonings resulting from an algal bloom in Nicaragua
During an October 2005 algal bloom (i.e., a rapid increase or accumulation in the population of algae) off the coast of Nicaragua, 45 people developed symptoms of paralytic shellfish poisoning (PSP) and one pe...
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Reference Work Entry In depth
Biotoxins and Food Safety
Foodborne illness in humans is an important global public health issue. This is primarily caused by pathogenic microorganisms (e.g., bacteria, fungi, parasites, and viruses) and toxins from natural source and ...
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Living Reference Work Entry In depth
Toxins and Food Safety
Foodborne illness in humans is an important global public health issue. This is primarily caused by pathogenic microorganisms (e.g., bacteria, fungi, parasites, and viruses) and toxins from natural source and ...
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Chapter
Occurrence of Cyanobacterial Harmful Algal Blooms Workgroup Report
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Chapter
Natural Toxins
Marine food products are generally wholesome, nutritious, healthful, and desirable. However, they may on occasion contain potent toxins of natural origin that could pose a significant threat to the health of c...
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Chapter
Blocking Pharmacology of Batrachotoxin-Activated Sodium Channels
Biochemical progress toward the mechanism of voltage-dependent Na+ channels has enjoyed the benefit of an extensive molecular pharmacology that includes natural specific toxins as well as synthetic chemical probe...