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Article
Delivery of local anaesthetics by a self-assembled supramolecular system mimicking their interactions with a sodium channel
Site-1 sodium channel blockers (S1SCBs) act as potent local anaesthetics, but they can cause severe systemic toxicity. Delivery systems can be used to reduce the toxicity, but the hydrophilicity of S1SCBs make...
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Article
Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units
Standard clinical care in neonatal and pediatric intensive-care units (NICUs and PICUs, respectively) involves continuous monitoring of vital signs with hard-wired devices that adhere to the skin and, in certa...
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Article
Ultrasound-triggered local anaesthesia
On-demand relief of local pain would allow patients to control the timing, intensity and duration of nerve blocks in a safe and non-invasive manner. Ultrasound would be a suitable trigger for such a system, as...