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Article
Open AccessMetabolomics reveals metabolites associated with hair follicle cycle in cashmere goats
The hair follicle is a skin accessory organ that regulates hair development, and its activity varies on a regular basis. However, the significance of metabolites in the hair follicle cycle has long been unknown.
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Article
Open AccessUnveiling the role of ABI3 and hub senescence-related genes in macrophage senescence for atherosclerotic plaque progression
Atherosclerosis, characterized by abnormal arterial lipid deposition, is an age-dependent inflammatory disease and contributes to elevated morbidity and mortality. Senescent foamy macrophages are considered to...
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Article
Open AccessDrivers of plateau adaptability in cashmere goats revealed by genomic and transcriptomic analyses
The adaptive evolution of plateau indigenous animals is a current research focus. However, phenotypic adaptation is complex and may involve the interactions between multiple genes or pathways, many of which re...
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Article
Comparative Analyses of the Gut Microbiome of Two Fox Species, the Red Fox (Vulpes Vulpes) and Corsac Fox (Vulpes Corsac), that Occupy Different Ecological Niches
The gut microbiome is integral for the host’s living and environmental adaptation and crucially important for understanding host adaptive mechanisms. The red fox (Vulpes vulpes) dominates a wider ecological niche...
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Article
Open AccessSingle-molecule long-read sequencing reveals the potential impact of posttranscriptional regulation on gene dosage effects on the avian Z chromosome
Mammalian sex chromosomes provide dosage compensation, but avian lack a global mechanism of dose compensation. Herein, we employed nanopore sequencing to investigate the genetic basis of gene expression and ge...
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Article
Open AccessInteraction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine
The liver plays an important role in production and metabolism of homocysteine (Hcy), which has been reported to be involved in liver injury. In our previous work, we confirm that Hcy can induce liver injury b...
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Article
Open AccessGenome-wide association analysis reveals that EDNRB2 causes a dose-dependent loss of pigmentation in ducks
Birds have various plumage color patterns, and spot is a common phenotype. Herein, we conducted genome-wide association studies (GWAS) in a population of 225 ducks with different sized black spots to reveal th...
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Article
Open AccessMolecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds
ATP-binding cassette (ABC) transporters are involved in the active transportation of various endogenous or exogenous substances. Two ABCG2 gene subfamily members have been identified in birds. A detailed comparat...
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Article
Open AccessA 14-bp insertion in endothelin receptor B-like (EDNRB2) is associated with white plumage in Chinese geese
Gang goose is a native species with gray plumage in Sichuan, China. As a result of overhunting, the number of gray Gang geese has decreased dramatically. To keep the species from extinction, conservation work ...
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Chapter and Conference Paper
Self-attention Based Collaborative Neural Network for Recommendation
With the rapid development of e-commerce, various types of recommendation systems have emerged in an endless stream
