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Article
Open AccessPatient-centricity in digital measure development: co-evolution of best practice and regulatory guidance
Digital health technologies (DHTs) have the potential to modernize drug development and clinical trial operations by remotely, passively, and continuously collecting ecologically valid evidence that is meaning...
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Article
Open AccessThe integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance
Changes in dopaminergic neuromodulation play a key role in adult memory decline. Recent research has also implicated noradrenaline in sha** late-life memory. However, it is unclear whether these two neuromod...
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Article
Open AccessMultimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial
We present data from the Heart Rate Variability and Emotion Regulation (HRV-ER) randomized clinical trial testing effects of HRV biofeedback. Younger (N = 121) and older (N = 72) participants completed baselin...
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Article
Correction: Effects of a Randomised Trial of 5-Week Heart Rate Variability Biofeedback Intervention on Cognitive Function: Possible Benefits for Inhibitory Control
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Article
Effects of a Randomised Trial of 5-Week Heart Rate Variability Biofeedback Intervention on Cognitive Function: Possible Benefits for Inhibitory Control
Previous research suggests that higher heart rate variability (HRV) is associated with better cognitive function. However, since most previous findings on the relationship between HRV and cognitive function we...
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Article
Increasing coordination and responsivity of emotion-related brain regions with a heart rate variability biofeedback randomized trial
Heart rate variability is a robust biomarker of emotional well-being, consistent with the shared brain networks regulating emotion regulation and heart rate. While high heart rate oscillatory activity clearly ...
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Article
A School–Hospital Partnership Increases Knowledge of Pedestrian and Motor Vehicle Safety
Pedestrian and motor vehicle-related injuries are leading causes of morbidity and mortality in children. Trauma centers have specialized resources to conduct interventions that improve the safety of whole comm...