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Article
Open AccessThe integrity of dopaminergic and noradrenergic brain regions is associated with different aspects of late-life memory performance
Changes in dopaminergic neuromodulation play a key role in adult memory decline. Recent research has also implicated noradrenaline in sha** late-life memory. However, it is unclear whether these two neuromod...
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Article
Open AccessSelf-reported and accelerometer-based assessment of physical activity in older adults: results from the Berlin Aging Study II
Physical activity (PA) has a substantial impact on health and mortality. Besides questionnaires that rely on subjective assessment of activity levels, accelerometers can help to objectify an individual’s PA. I...
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Article
Open AccessAuthor Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
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Article
Open AccessAsymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
Aging and Alzheimer’s disease (AD) are associated with progressive brain disorganization. Although structural asymmetry is an organizing feature of the cerebral cortex it is unknown whether continuous age- and...
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Reference Work Entry In depth
Berlin Aging Study II (BASE-II)
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Article
Open AccessRelationship between Lipoprotein (a) and cognitive function – Results from the Berlin Aging Study II
It has been suggested that an age-related loss of cognitive function might be driven by atherosclerotic effects associated with altered lipid patterns. However, the relationship between Lipoprotein (a) [Lp(a)]...
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Article
Rostral locus coeruleus integrity is associated with better memory performance in older adults
For decades, research into memory decline in human cognitive ageing has focused on neocortical regions, the hippocampus and dopaminergic neuromodulation. Recent findings indicate that the locus coeruleus (LC) ...
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Article
Open AccessStructural Brain Correlates of Loneliness among Older Adults
Ample evidence indicates that loneliness in old age is associated with poor bodily and mental health. However, little is known about structural cerebral correlates of loneliness in healthy older adults. We exa...
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Article
Open AccessFood for thought: association between dietary tyrosine and cognitive performance in younger and older adults
The fact that tyrosine increases dopamine availability that, in turn, may enhance cognitive performance has led to numerous studies on healthy young participants taking tyrosine as a food supplement. As a resu...
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Living Reference Work Entry In depth
Berlin Aging Study II (BASE-II)
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Article
Feeling older, walking slower—but only if someone’s watching. Subjective age is associated with walking speed in the laboratory, but not in real life
The huge inter-individual differences in how people age have prompted researchers to examine whether people’s own perception of how old they are—their subjective age—could be a better predictor of relevant out...
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Article
Open AccessIn search of features that constitute an “enriched environment” in humans: Associations between geographical properties and brain structure
Enriched environments elicit brain plasticity in animals. In humans it is unclear which environment is enriching. Living in a city has been associated with increased amygdala activity in a stress paradigm, and...
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Reference Work Entry In depth
Berlin Aging Studies (BASE and BASE-II)
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Living Reference Work Entry In depth
Berlin Aging Studies (BASE and BASE-II)
