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Article
Racial and Ethnic Disparity for Cancer Mortality in General and Single-Payer Healthcare Systems in the United States
It remains unclear what factors significantly drive racial disparity in cancer survival in the United States (US). We compared adjusted mortality outcomes in cancer patients from different racial and ethnic gr...
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Article
Safety evaluation of biopolymer immune implants in rats and rabbits as well as therapeutic effects on gastric cancer peritoneal metastasis carcinoma
Peritoneal metastasis carcinoma (PMC), as an extremely aggressive malignant tumor with high metastatic potential, typically exhibits an average clinical survival period of less than 9 months. Unfortunately, th...
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Article
Open AccessClinical Analysis of Y Chromosome Microdeletions and Chromosomal Aberrations in 1596 Male Infertility Patients of the Zhuang Ethnic Group in Guangxi
The long arm of the Y chromosome (Yq) contains many amplified and palindromic sequences that are prone to self-reorganization during spermatogenesis, and tiny submicroscopic segmental deletions in the proximal...
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Article
Covalent triazine frameworks modified by ultrafine Pt nanoparticles for efficient photocatalytic hydrogen production
Pt nanoparticles (PtNPs) as active species have always been considered as one of the best semiconductor materials for photocatalytic hydrogen production. In this study, a Schottky heterojunction has been succe...
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Article
Variation in TaSPL6-D confers salinity tolerance in bread wheat by activating TaHKT1;5-D while preserving yield-related traits
Na+ exclusion from above-ground tissues via the Na+-selective transporter HKT1;5 is a major salt-tolerance mechanism in crops. Using the expression genome-wide association study and yeast-one-hybrid screening, we...
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Article
Open AccessRevisiting the role of pregnancy zone protein (PZP) as a cancer biomarker in the immunotherapy era
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Article
Open AccessIntegrating blockchain and ZK-ROLLUP for efficient healthcare data privacy protection system via IPFS
With the rapid development of modern medical technology and the dramatic increase in the amount of medical data, traditional centralized medical information management is facing many challenges. In recent year...
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Article
ITGB4 is a prognostic biomarker and correlated with lung adenocarcinoma brain metastasis
The aim of this study is to explore the prognostic value and immune signature of ITGB4 expression in lung adenocarcinoma (LUAD) brain metastasis.
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Article
Open AccessMetabolomics reveals metabolites associated with hair follicle cycle in cashmere goats
The hair follicle is a skin accessory organ that regulates hair development, and its activity varies on a regular basis. However, the significance of metabolites in the hair follicle cycle has long been unknown.
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Article
Damage identification of non-dispersible underwater concrete columns under compression using impedance technique and stress-wave propagation
Current scouring effects and additives increase the risk of failure in underwater structures, and poor observation complicates the identification and assessment of damage. We present a novel index for assessin...
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Article
Natural variant of Rht27, a dwarfing gene, enhances yield potential in wheat
Discovery of Rht27, a dwarf gene in wheat, showed potential in enhancing grain yield by reducing plant height.
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Article
Photoelectrochemical sensing of isoniazid and streptomycin based on metal Bi-doped BiOI microspheres grown on book-shape layers of Ti3C2 heterostructures
Isoniazid and streptomycin are vital drugs for treating tuberculosis, which are utilized as efficient anti-tuberculosis agents. This paper presents a novel visible-light-driven composite photocatalyst Ti3C2/Bi/B...
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Article
Open AccessProbing altered receptor specificities of antigenically drifting human H3N2 viruses by chemoenzymatic synthesis, NMR, and modeling
Prototypic receptors for human influenza viruses are N-glycans carrying α2,6-linked sialosides. Due to immune pressure, A/H3N2 influenza viruses have emerged with altered receptor specificities that bind α2,6-lin...
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Article
Open AccessEngineering the pore environment of antiparallel stacked covalent organic frameworks for capture of iodine pollutants
Radioiodine capture from nuclear fuel waste and contaminated water sources is of enormous environmental importance, but remains technically challenging. Herein, we demonstrate robust covalent organic framework...
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Article
Open AccessInfluence of coal cowl parameters on the coal loading process of thin coal seam shearer drum
The low loading rate of the thin coal seam shearer drum is a severe obstacle to the efficient mining of thin seam resources, and the auxiliary drum loading through the cowl is an effective measure to alleviate...
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Article
Trends in the prevalence and risk factors for peripherally inserted central catheter-related complications in cancer patients from 2016 to 2022: a multicenter study
To identify the trends in the prevalence of peripherally inserted central catheter (PICC) related complications in cancer patients and explore the risk factors for complications and occurrence speed.
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Article
Pharmacokinetics, mass balance, and metabolism of [14C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects
Envonalkib (TQ-B3139) is a novel, potent anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor used to treat ALK-positive non-small cell lung cancer. This phase I mass balance study investigated the pharm...
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Article
Compulsory education and gender gaps in intrahousehold empowerment
This paper estimates the effects of China’s 1986 Compulsory Education Law (CEL) on gender gaps in intrahousehold empowerment. The analysis uses a province-level dataset compiled from the population census and ...
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Article
Transcriptome analysis of the bloom-forming dinoflagellate Prorocentrum donghaiense exposed to Ginkgo biloba leaf extract, with an emphasis on photosynthesis
Ginkgo biloba leaf extract (GBE) can effectively treat bloom-forming freshwater algae. However, there is limited information about the underlying suppression mechanism of the marine bloom-forming Prorocentrum do...
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Article
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway
Non-small cell lung cancer (NSCLC) contributes to the vast majority of cancer-related deaths. Proteasome 26S subunit, non-ATPase 12 (PSMD12), a subunit of 26S proteasome complex, is known to play the tumor-pro...
