-
Article
Open AccessComprehensive multiomics analysis reveals distinct differences between pediatric choroid plexus papilloma and carcinoma
Choroid plexus tumors (CPTs) are intraventricular tumors derived from the choroid plexus epithelium and occur frequently in children. The aim of this study was to investigate the genomic and epigenomic charact...
-
Article
The role of surgery for optic pathway gliomas in the era of precision medicine
Optic pathway gliomas (OPGs) represent a unique subset of brain tumours that primarily affect the paediatric population. Traditionally, these tumours are managed conservatively due to their location to and ass...
-
Article
Surgical treatment of interhemispheric arachnoid cysts
In children, interhemispheric arachnoid cysts (IHACs) are rare lesions often associated with corpus callosum dysgenesis. It is still controversial about surgical treatments for IHACs. We aim to report our expe...
-
Article
Fibrous hamartoma of infancy of the spinal cord resembling conus and filum, with a coexisting sacral dimple
Fibrous hamartoma of infancy (FHI) is a rare benign soft tissue lesion of infants and young children. It usually occurs within the first 2 years of life at the superficial layer of the axilla, trunk, upper arm...
-
Article
Open AccessGrowth patterns of young achondroplasia patients in Korea and predictability of neurosurgical procedures
Achondroplasia is an autosomal dominant disorder mainly affecting bony growth, typically resulting in markedly short stature. From a neurosurgical viewpoint, patients sometimes develop spinal cord compression ...
-
Article
Technical evolution of pediatric neurosurgery: moyamoya disease
Moyamoya disease (MMD) is a rare steno-occlusive disease of the bilateral internal carotid arteries that predominantly occurs in East Asia. Since the first description of the MMD by Suzuki and Takaku in 1969, ...
-
Article
Ultra-low-dose computed tomography with deep learning reconstruction for craniosynostosis at radiation doses comparable to skull radiographs: a pilot study
Craniofacial computed tomography (CT) is the diagnostic investigation of choice for craniosynostosis, but high radiation dose remains a concern.
-
Article
Endoscopic biopsy of pineal tumors: two burr hole trans-foramen of Monro approach and endonasal trans-tuber cinereum approach
The pineal region is a challenging area for neurosurgeons due to its innate anatomical features, such as its deep location, surrounding large draining veins, and adjacent critical neural structures.
-
Article
Comparison of the clinical features and treatment outcomes of pilocytic astrocytoma in pediatric and adult patients
Pilocytic astrocytoma is a slow-growing tumor that predominantly develops in children, but has a broad age spectrum. A notable characteristic of pilocytic astrocytoma is that the tumor arises in diverse locati...
-
Article
Correction to: Myelomeningocele as an anomaly of secondary neurulation
-
Article
Open AccessAuthor Correction: Genomic analysis as a tool to infer disparate phylogenetic origins of dysembryoplastic neuroepithelial tumors and their satellite lesions
-
Article
Open AccessGenomic analysis as a tool to infer disparate phylogenetic origins of dysembryoplastic neuroepithelial tumors and their satellite lesions
Dysembryoplastic neuroepithelial tumor (DNET) is a low-grade brain tumor commonly associated with drug-resistant epilepsy. About half of DNETs are accompanied by tiny nodular lesions separated from the main ma...
-
Article
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation
-
Article
Open AccessMolecular subgrou** of medulloblastoma in pediatric population using the NanoString assay and comparison with immunohistochemistry methods
Molecular subgrou** of medulloblastoma has become important due to its impact on risk group stratification. Immunohistochemistry (IHC) has been widely used but it has innate limitations. The NanoString assay...
-
Article
Myelomeningocele as an anomaly of secondary neurulation
Myelomeningocele (MMC) is the representative entity of open neural tube defects resulting from an error during primary neurulation. However, cases of MMC in the region of the secondary neural tube (below the j...
-
Article
Outcomes of intracranial non-germinomatous germ cell tumors: a retrospective Asian multinational study on treatment strategies and prognostic factors
Non-germinomatous germ cell tumors (NGGCTs) are rare pediatric conditions. This multicenter study using Asian multinational patient data investigated treatment outcomes and prognostic factors for NGGCTs.
-
Article
Failure of human rhombic lip differentiation underlies medulloblastoma formation
Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain1–4. Mutations that activate Sonic hedgehog signallin...
-
Article
Open AccessThe telomere maintenance mechanism spectrum and its dynamics in gliomas
The activation of the telomere maintenance mechanism (TMM) is one of the critical drivers of cancer cell immortality. In gliomas, TERT expression and TERT promoter mutation are considered to reliably indicate tel...
-
Article
Emerging glioneuronal and neuronal tumors: case-based review
Glioneuronal and neuronal tumors (GNTs) are rare heterogeneous central nervous system tumors characterized by slow growth and favorable outcomes, but are often associated with diagnostic difficulties. A thorou...
-
Article
Identification of preferential target sites for the environmental flow estimation using a simple flowchart in Korea
Since the 1960s, rapid urbanization has caused serious deterioration in the quantity and quality of instream flows in South Korea. As demands for healthy instream ecology, landscape, and water-friendly environ...
