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  1. No Access

    Article

    Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer

    Epithelial-mesenchymal transition (EMT) is a driving force in promoting malignant cancer, including initiation, growth, and metastasis. EMT is a dynamic process that can undergo a mesenchymal-epithelial transi...

    Hector Esquer, Qiong Zhou, Travis Nemkov, Adedoyin D. Abraham in Oncogene (2021)

  2. Article

    Open Access

    Subtype specific expression and survival prediction of pivotal lncRNAs in muscle invasive bladder cancer

    Comprehensive transcriptome expression analyses of bladder cancer revealed distinct lncRNA clusters with differential molecular and clinical characteristics. In this study, pivotal lncRNAs were assessed for th...

    Sebastien Rinaldetti, Thomas Stefan Worst, Eugen Rempel in Scientific Reports (2020)

  3. Article

    Correction: High-risk additional chromosomal abnormalities at low blast counts herald death by CML

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Rüdiger Hehlmann, Astghik Voskanyan, Michael Lauseker, Markus Pfirrmann in Leukemia (2020)

  4. Article

    Open Access

    High-risk additional chromosomal abnormalities at low blast counts herald death by CML

    Blast crisis is one of the remaining challenges in chronic myeloid leukemia (CML). Whether additional chromosomal abnormalities (ACAs) enable an earlier recognition of imminent blastic proliferation and a time...

    Rüdiger Hehlmann, Astghik Voskanyan, Michael Lauseker, Markus Pfirrmann in Leukemia (2020)

  5. Article

    Open Access

    FOXM1 predicts disease progression in non-muscle invasive bladder cancer

    The proto-oncogene forkhead box M1 (FOXM1) is associated with poor survival in many cancers. The impact of FOXM1 expression on progression-free survival (PFS) of non-muscle invasive bladder cancer (NMIBC) has ...

    Sebastien Rinaldetti, Ralph Wirtz in Journal of Cancer Research and Clinical On… (2018)

  6. Article

    Open Access

    Defining therapy goals for major molecular remission in chronic myeloid leukemia: results of the randomized CML Study IV

    Major molecular remission (MMR) is an important therapy goal in chronic myeloid leukemia (CML). So far, MMR is not a failure criterion according to ELN management recommendation leading to uncertainties when t...

    Susanne Saussele, Rüdiger Hehlmann, Alice Fabarius, Sabine Jeromin in Leukemia (2018)

  7. No Access

    Article

    Impact of unbalanced minor route versus major route karyotypes at diagnosis on prognosis of CML

    Major route additional cytogenetic aberrations (ACA) at diagnosis of chronic myeloid leukaemia (CML) indicate an increased risk of progression and shorter survival. Since major route ACA are almost always unba...

    Alice Fabarius, Lida Kalmanti, Christian T. Dietz, Michael Lauseker in Annals of Hematology (2015)