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Article
Correction: High-risk additional chromosomal abnormalities at low blast counts herald death by CML
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessHigh-risk additional chromosomal abnormalities at low blast counts herald death by CML
Blast crisis is one of the remaining challenges in chronic myeloid leukemia (CML). Whether additional chromosomal abnormalities (ACAs) enable an earlier recognition of imminent blastic proliferation and a time...
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Article
Impact of unbalanced minor route versus major route karyotypes at diagnosis on prognosis of CML
Major route additional cytogenetic aberrations (ACA) at diagnosis of chronic myeloid leukaemia (CML) indicate an increased risk of progression and shorter survival. Since major route ACA are almost always unba...
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Article
Open AccessOlder patients with chronic myeloid leukemia (≥65 years) profit more from higher imatinib doses than younger patients: a subanalysis of the randomized CML-Study IV
The impact of imatinib dose on response rates and survival in older patients with chronic myeloid leukemia in chronic phase has not been studied well. We analyzed data from the German CML-Study IV, a randomize...
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Article
Open AccessYounger patients with chronic myeloid leukemia do well in spite of poor prognostic indicators: results from the randomized CML study IV
Since the advent of tyrosine kinase inhibitors, the impact of age on outcome of chronic myeloid leukemia (CML) patients has changed. We therefore analyzed patients from the randomized CML study IV to investiga...
