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  1. Article

    Open Access

    T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure

    We investigated whether CD4+-T cells with specificity for an antigen in cardiomyocytes promote the progression from hypertrophy to heart failure in mice with increased pressure load due to transverse aortic const...

    Carina Gröschel, André Sasse, Charlotte Röhrborn, Sebastian Monecke… in Scientific Reports (2017)

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  2. Article

    Open Access

    The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA

    The MHC class I chain-related molecule A (MICA) is a ligand for the activating natural killer (NK) cell receptor NKG2D. A polymorphism causing a valine to methionine exchange at position 129 affects binding to...

    Antje Isernhagen, Daniela Schilling, Sebastian Monecke, Pranali Shah… in Immunogenetics (2016)

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  3. Article

    Open Access

    Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules

    Multipotent adult germ-line stem cells (maGSCs) represent a new pluripotent cell type that can be derived without genetic manipulation from spermatogonial stem cells (SSCs) present in adult testis. Similarly t...

    Ralf Dressel, Kaomei Guan, Jessica Nolte, Leslie Elsner… in Biology Direct (2009)

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