-
Article
Open AccessThousands of previously unknown phages discovered in whole-community human gut metagenomes
Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in structuring human gut microbiomes; yet, the gut virome is far from being fully characterized, and additional groups of phages, including ...
-
Article
Open AccessAnalysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features
CrAssphage is the most abundant human-associated virus and the founding member of a large group of bacteriophages, discovered in animal-associated and environmental metagenomes, that infect bacteria of the phy...
-
Article
Open AccessGenomic and ecological attributes of marine bacteriophages encoding bacterial virulence genes
Bacteriophages encode genes that modify bacterial functions during infection. The acquisition of phage-encoded virulence genes is a major mechanism for the rise of bacterial pathogens. In coral reefs, high bac...
-
Article
Open AccessA diversity-generating retroelement encoded by a globally ubiquitous Bacteroides phage
Diversity-generating retroelements (DGRs) are genetic cassettes that selectively mutate target genes to produce hypervariable proteins. First characterized in Bordetella bacteriophage BPP-1, the DGR creates a hyp...
