31 Result(s)
-
Article
Open AccessAn online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice: protocol for a feasibility study in preparation for a future cluster randomised controlled trial
This feasibility study for a future definitive randomized trial assesses the use and acceptability of a new clinical decision tool to identify risk of a vertebral fracture and those who should be referred for ...
-
Article
Further advances in epilepsy
In 2017, one of us reviewed advances in epilepsy (Manford in J Neurol 264:1811–1824, 2017). The current paper brings that review up to date and gives a slight change in emphasis. Once again, the story is of ev...
-
Article
Research priorities regarding the use of bisphosphonates for osteoporosis: a UK priority setting exercise
Worldwide, many people who would benefit from osteoporosis drugs are not offered or receiving them, resulting in an osteoporosis care gap. Adherence with bisphosphonates is particularly low. This study aimed t...
-
Article
Open AccessExperiential Avoidance in Advanced Cancer: a Mixed-Methods Systematic Review
People with advanced cancer experience psychological distress due to physical symptoms, functional decline, and a limited prognosis. Difficult thoughts, feelings, and emotions may exacerbate distress and lead ...
-
Article
Open AccessDevelo** catalyst films of health experiences: an analysis of a robust multi-stakeholder involvement journey
Those whose lives are most directly impacted by health care—patients, caregivers, and frontline staff—are ideally situated to improve patient health care services and care quality. Despite a proliferation of l...
-
Article
Open AccessDo palliative care patients and relatives think it would be acceptable to use Bispectral index (BIS) technology to monitor palliative care patients’ levels of consciousness? A qualitative exploration with interviews and focus groups for the I-CAN-CARE research programme
Bispectral index (BIS) monitoring uses electroencephalographic data as an indicator of patients’ consciousness level. This technology might be a useful adjunct to clinical observation when titrating sedative m...
-
Article
Review of Evidence-Based Approaches to Caregiver Training
Training caregivers on tasks related to quality of life for the individuals they support is important across service sectors. Moreover, trainees often rank quality training as highly acceptable. This review su...
-
Article
Open AccessContext, mechanisms and outcomes in end-of-life care for people with advanced dementia: family carers perspective
Kee** people living with advanced dementia in their usual place of residence is becoming a key governmental goal but to achieve this, family carers and health care professionals must negotiate how to provide...
-
Article
Addiction to Self-harm? The Case of Online Postings on Self-harm Message Boards
Presently, there is limited research investigating the addictive nature of self-harm, even though non-suicidal self-injury disorder has been included in the DSM-V (American Psychiatric Association 2013) for over ...
-
Article
Pirfenidone for Treating Idiopathic Pulmonary Fibrosis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
The National Institute for Health and Care Excellence (NICE) published guidance on the use of pirfenidone (Esbriet®, Roche) for the treatment of mild to moderate idiopathic pulmonary fibrosis (IPF) in 2013. NICE ...
-
Article
Open AccessCorrection to: Economic Evaluations Alongside Efficient Study Designs Using Large Observational Datasets: the PLEASANT Trial Case Study
The original article can be found online.
-
Article
Open AccessDevelo** primary care teams prepared to improve quality: a mixed-methods evaluation and lessons learned from implementing a microsystems approach
Health systems in the United States are increasingly required to become leaders in quality to compete successfully in a value-conscious purchasing market. Doing so involves develo** effective clinical teams ...
-
Article
Obinutuzumab with Bendamustine for Treating Follicular Lymphoma Refractory to Rituximab: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
As part of its single technology appraisal process, the UK National Institute for Health and Care Excellence (NICE) invited the manufacturer of obinutuzumab (Roche) to submit evidence on its clinical and cost ...
-
Article
Re: The Ottawa Self-injury Inventory Version 3.1: Suggestions for Revision to the Addictive Features Section
-
Article
Validation of a DICE Simulation Against a Discrete Event Simulation Implemented Entirely in Code
Modeling is an essential tool for health technology assessment, and various techniques for conceptualizing and implementing such models have been described. Recently, a new method has been proposed—the discret...
-
Article
Open AccessExperiences of end of life amongst family carers of people with advanced dementia: longitudinal cohort study with mixed methods
Many studies have examined the mental health of carers of people with dementia. Few have examined their experiences in the advanced stages of disease and into bereavement. We aimed to understand the experience...
-
Article
Open AccessEconomic Evaluations Alongside Efficient Study Designs Using Large Observational Datasets: the PLEASANT Trial Case Study
Large observational datasets such as Clinical Practice Research Datalink (CPRD) provide opportunities to conduct clinical studies and economic evaluations with efficient designs.
-
Article
Open AccessAn ethnographic study of strategies to support discussions with family members on end-of-life care for people with advanced dementia in nursing homes
Most people with advanced dementia die in nursing homes where families may have to make decisions as death approaches. Discussions about end-of-life care between families and nursing home staff are uncommon, d...
-
Article
Open AccessThe clinical and cost effectiveness of cognitive behavioural therapy plus treatment as usual for the treatment of depression in advanced cancer (CanTalk): study protocol for a randomised controlled trial
The prevalence of depressive disorder in adults with advanced cancer is around 20 %. Although cognitive behavioural therapy (CBT) is recommended for depression and may be beneficial in depressed people with ca...
-
Article
Open AccessAcceptance and commitment therapy for adults with advanced cancer (CanACT): study protocol for a feasibility randomised controlled trial
One-third of people with cancer experience psychological distress and may suppress distressing thoughts, emotions, and concerns, leading to further problems. Conventional psychological treatments reduce distre...
