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  1. No Access

    Article

    Genetic repression of the antioxidant enzymes reduces the lifespan in Drosophila melanogaster

    Aging is a biological process associated with gradual loss of function caused by cellular and molecular damages ultimately leading to mortality. Free radicals are implicated in oxidative damage which affects t...

    S. Deepashree, T. Shivanandappa, Saraf R. Ramesh in Journal of Comparative Physiology B (2022)

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    Article

    In vivo peritoneal antiangiogenesis and in vitro antiproliferative properties of some bischalcone derivatives

    In this study, three, bisarylidene cyclopentanones (curcumin analogs) 3a–c are synthesized by Claisen Schmidt condensation reaction. Antiangiogenic effects of the compounds were studied in Ehrlich ascites tumor (...

    Chenna Govindaraju Darshan Raj, Balladaka Kunhanna Saro**i… in Medicinal Chemistry Research (2012)

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    Article

    Attenuation of Rotenone-Induced Mitochondrial Oxidative Damage and Neurotoxicty in Drosophila melanogaster Supplemented with Creatine

    Creatine (Cr), an ergogenic nutritional supplement is demonstrated to possess bioenergetic, antiexcitotoxic and antioxidant properties. This study investigated the neuroprotective effects of Cr against rotenon...

    Ravikumar Hosamani, Saraf R. Ramesh, Muralidhara in Neurochemical Research (2010)