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Article
Open AccessComparison of Four Protocols for In Vitro Differentiation of Human Embryonic Stem Cells into Trophoblast Lineages by BMP4 and Dual Inhibition of Activin/Nodal and FGF2 Signaling
Human embryonic stem cells (hESCs) cultured in media containing bone morphogenic protein 4 (BMP4; B) differentiate into trophoblast-like cells. Supplementing media with inhibitors of activin/nodal signaling (A...
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Article
Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B
The subcortical maternal complex (SCMC) is a multiprotein complex in oocytes and preimplantation embryos that is encoded by maternal effect genes. The SCMC is essential for zygote-to-embryo transition, early e...
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Article
Open AccessPsychiatric, cognitive functioning and socio-cultural views of menstrual psychosis in Oman: an idiographic approach
Most documented cases of menstrual psychosis have been from Euro-American populations with reports from cross-cultural populations being only a few. A primary aim was to determine whether the cyclical/episodic...
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Article
Open AccessErratum: Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming
Scientific Reports 7: Article number: 44667; published online: 20 March 2017; updated: 19 April 2017 The original version of this Article contained an incorrect affiliation list. The correct affiliations are l...
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Article
Open AccessMaternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming
Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition ...
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Article
Automating factory performance diagnostics using overall throughput effectiveness (OTE) metric
The overall equipment effectiveness (OEE) metric is a powerful tool that can be used to measure performance and also perform diagnostics at the equipment level. Although important, gains made in OEE are insuff...
