5 Result(s)
within
Samantha Burnham
English
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Article
Open AccessRelationship between amyloid and tau levels and its impact on tau spreading
Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the neocortex is still unclear.
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Chapter
Aβ Imaging in Aging, Alzheimer’s Disease, and Other Neurodegenerative Conditions
In vivo imaging of β-amyloid (Αβ) has transformed the assessment of Αβ pathology and its changes over time, extending our insight into Aβ deposition in the brain by providing highly accurate, reliable, and rep...
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Chapter and Conference Paper
Identification of Functional Connectivity Features in Depression Subtypes Using a Data-Driven Approach
Biomarkers are not well understood in depression, partly because there is no golden rule of what is abnormal in which patients and how neurobiological information can be used to improve diagnosis. The heteroge...
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Article
Open AccessInsulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults
Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of develo** dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance ...
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Article
Open AccessFollow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort
Alzheimer’s disease (AD) is a growing socioeconomic problem worldwide. Early diagnosis and prevention of this devastating disease have become a research priority. Consequently, the identification of clinically...
