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Aβ Imaging in Aging, Alzheimer’s Disease, and Other Neurodegenerative Conditions

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  1. Article

    Open Access

    Relationship between amyloid and tau levels and its impact on tau spreading

    Previous studies have shown that Aβ-amyloid (Aβ) likely promotes tau to spread beyond the medial temporal lobe. However, the Aβ levels necessary for tau to spread in the neocortex is still unclear.

    Vincent Doré, Natasha Krishnadas in European Journal of Nuclear Medicine and M… (2021)

  2. Article

    Open Access

    Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults

    Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of develo** dementia. Experimental evidence from mouse models demonstrates that the induction of T2D/insulin resistance ...

    Simon M. Laws, Scott Gaskin, Amy Woodfield, Velandai Srikanth in Scientific Reports (2017)

  3. Article

    Open Access

    Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort

    Alzheimer’s disease (AD) is a growing socioeconomic problem worldwide. Early diagnosis and prevention of this devastating disease have become a research priority. Consequently, the identification of clinically...

    Veer B Gupta, Andrea C Wilson, Samantha Burnham in Alzheimer's Research & Therapy (2015)