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    Article

    Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

    Phosphorylation of p53 at Ser 46 was shown to regulate p53 apoptotic activity. Here we demonstrate that homeodomain-interacting protein kinase-2 (HIPK2), a member of a novel family of nuclear serine/threonine ...

    Gabriella D'Orazi, Barbara Cecchinelli, Tiziana Bruno… in Nature Cell Biology (2002)

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    Article

    The role of wild-type p53 in the differentiation of primary hemopoietic and muscle cells

    Experiments previously performed on 32D and C2C12 cell lines indicated that wild type p53 (wtp53) protein has a role in granulocyte and myotube differentiation. Since these are immortal cells, we asked whether...

    Giuseppina Mazzaro, Gianluca Bossi, Sabrina Coen, Ada Sacchi, Silvia Soddu in Oncogene (1999)