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  1. Article

    Open Access

    Elastin peptides regulate HT-1080 fibrosarcoma cell migration and invasion through an Hsp90-dependent mechanism

    The elastin-derived peptides (EDPs) exert protumoural activities by potentiating the secretion of matrix metalloproteinases (MMP) and the plasminogen–plasmin activating system. In the present paper, we studied...

    M Donet, S Brassart-Pasco, S Salesse, F-X Maquart, B Brassart in British Journal of Cancer (2014)

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  2. No Access

    Article

    Tissue inhibitor of metalloproteinase-1 promotes hematopoietic differentiation via caspase-3 upstream the MEKK1/MEK6/p38α pathway

    Besides its matrix metalloproteinases inhibitory activity, TIMP-1 exhibits other biological activities such as cell survival and proliferation. The intracellular signalling pathway elicited by TIMP-1 begins to...

    E Dassé, L Bridoux, T Baranek, E Lambert, S Salesse, M L Sowa, L Martiny… in Leukemia (2007)

  3. No Access

    Article

    BCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cells

    The mechanism underlying p210BCR/ABL oncoprotein-mediated transformation in chronic myelogenous leukemia (CML) is not fully understood. We hypothesized that p210BCR/ABL suppresses expression of genes which may ex...

    M Jongen-Lavrencic, S Salesse, R Delwel, C M Verfaillie in Leukemia (2005)

  4. No Access

    Article

    p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells

    Chronic myelogenous leukemia (CML) is a malignancy of the human hematopoietic stem cell (HSC) caused by the p210BCR/ABL oncoprotein. Although alternative splicing of pre-mRNA is a critical determinant of a cell's...

    S Salesse, S J Dylla, C M Verfaillie in Leukemia (2004)

  5. No Access

    Article

    Rapid analysis and efficient selection of human transduced primitive hematopoietic cells using the humanized S65T green fluorescent protein

    We have developed an efficient and rapid method to analyze transduction in human hematopoietic cells and to select them. We constructed two retroviral vectors using the recombinant humanized S65T green fluores...

    F Mazurier, F Moreau-Gaudry, V Maguer-Satta, S Salesse… in Gene Therapy (1998)

  6. No Access

    Article

    Gene transfer of the uroporphyrinogen III synthase cDNA into haematopoietic progenitor cells in view of a future gene therapy in congenital erythropoietic porphyria

    Congenital erythropoietic porphyria (CEP) is an inherited metabolic disorder characterized by an overproduction and accumulation of porphyrins in bone marrow. This autosomal recessive disease results from a de...

    F. Mazurier, F. Moreau-Gaudry, S. Salesse… in Journal of Inherited Metabolic Disease (1997)