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  1. No Access

    Article

    Ring-substituted analogs of 3,3′-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and –independent prostate cancer cells

    We recently reported that novel ring-substituted analogs of 3,3′-diindolylmethane (ring-DIMs) have anti-androgenic and growth inhibitory effects in androgen-dependent prostate cancer cells. The objectives of t...

    A. A. Goldberg, V. I. Titorenko, A. Beach, K. Abdelbaqi… in Investigational New Drugs (2014)

  2. No Access

    Article

    HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

    HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor survival for breast, colon and liver cancer patien...

    K Kim, I Jutooru, G Chadalapaka, G Johnson, J Frank, R Burghardt, S Kim, S Safe in Oncogene (2013)

  3. Article

    Erratum: The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53

    Correction to: Oncogene (2012) 31, 3265–3276; doi:10.1038/onc.2011.504; published online 14 November 2011 Since the publication of the above manuscript the authors have identified an error in the author list; ...

    S-O Lee, T Andey, U-H **, K Kim, M Singh, S Safe in Oncogene (2012)

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  4. No Access

    Article

    The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53

    The orphan nuclear receptor TR3 (NR41A and Nur77) is overexpressed in most lung cancer patients and is a negative prognostic factor for patient survival. The function of TR3 was investigated in non-small-cell ...

    S-O Lee, T Andey, U-H **, K Kim, M Sachdeva, S Safe in Oncogene (2012)

  5. No Access

    Article

    Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer

    The human POK family members are transcription factors with a POZ domain and zinc-fingers that act primarily as transcriptional repressors. Several members of this family are involved in oncogenesis and this p...

    K Kim, G Chadalapaka, S-O Lee, D Yamada, X Sastre-Garau, P-A Defossez, Y-Y Park… in Oncogene (2012)

  6. No Access

    Article

    Antiestrogenic activities of alternate-substituted polychlorinated dibenzofurans in MCF-7 human breast cancer cells

    Purpose: 1,3,6,8-Substituted alkyl polychlorinated dibenzofurans (PCDFs), typified by 6-methyl-1,3,8-triCDF (MCDF), inhibit 17β-estradiol (E2)-induced responses in the rodent uterus and human breast cancer cells...

    Gulan Sun, S. Safe in Cancer Chemotherapy and Pharmacology (1997)

  7. No Access

    Article

    Effect of transient expression of the oestrogen receptor on constitutive and inducible CYP1A1 in Hs578T human breast cancer cells

    Hs578T human breast cancer cells are an oestrogen receptor (ER)-negative cell line. Treatment of these cells with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) resulted in formation of a 6.9 S nuclear aryl hydroc...

    WL Wang, JS Thomsen, W Porter, M Moore, S Safe in British Journal of Cancer (1996)