17 Result(s)

Article

OnabotulinumtoxinA in elderly patients with chronic migraine: insights from a real-life European multicenter study

Although migraine prevalence decreases with aging, some older patients still suffer from chronic migraine (CM). This study aimed to investigate the outcome of OnabotulinumtoxinA (OBT-A) as preventative therapy...

Claudia Altamura, R. Ornello, F. Ahmed, A. Negro, A. M. Miscio… in Journal of Neurology (2023)

Article

Heritable and non-heritable uncommon causes of stroke

Despite intensive investigations, about 30% of stroke cases remains of undetermined origin. After exclusion of common causes of stroke, there is a number of rare heritable and non-heritable conditions, which o...

A. Bersano, M. Kraemer, A. Burlina, M. Mancuso, J. Finsterer… in Journal of Neurology (2021)

Article

Late-onset Pompe disease: a genetic-radiological correlation on cerebral vascular anomalies

Pompe disease is an autosomal recessive disorder in which deficiency of the lysosomal enzyme acid alpha-glucosidase results in the accumulation of glycogen mostly in muscle tissues. Several reports suggest a h...

A. Pichiecchio, S. Sacco, P. De Filippi, E. Caverzasi, S. Ravaglia… in Journal of Neurology (2017)

Chapter

Cardio-cerebrovascular Comorbidity

Migraine, particularly migraine with aura has been associated with an increased risk of vascular events including ischemic and hemorrhagic stroke, myocardial infarction, and angina. Data also indicated that mi...

S. Sacco, C. Bushnell in Comorbidities in Headache Disorders (2017)

Article

The -308 TNFα and the -174 IL-6 promoter polymorphisms associate with effective anti-TNFα treatment in seronegative spondyloarthritis

The genetic predisposition to a long-term efficacy of anti-tumor necrosis factor (TNF)α treatment in seronegative spondyloarthritis (SpA) was investigated by analysing the possible correlation between several ...

M Fabris, L Quartuccio, C Fabro, S Sacco, S Lombardi… in The Pharmacogenomics Journal (2016)

Article

Optimizing the dose of mycophenolate mofetil for the maintenance treatment of lupus nephritis by therapeutic drug monitoring

To evaluate the usefulness of monitoring the pharmacokinetic of mycophenolic acid (MPA) in lupus nephritis (LN), in order to optimize the mycophenolate mofetil (MMF) dose in the single patient. Five consecutiv...

A. Zabotti, M. Baraldo, L. Quartuccio, S. Sacco, G. De Marchi… in Clinical Rheumatology (2015)

Article

A simplified indication of metabolic syndrome to recognize subjects with a moderate risk to develop type 2 diabetes mellitus in a large Italian sample

To propose a simplified tool to recognize subjects with a moderate risk to develop type 2 diabetes mellitus (Type 2 DM): this method would take into account only variables from metabolic syndrome definitions w...

S. Sacco, M. Comelli, V. Molina, P. L. Montrasio, E. Giani… in Acta Diabetologica (2014)

Article

Homocysteine and leukoaraiosis: time for a clinical trial?

S. Sacco, A. Carolei in Neurological Sciences (2007)

Article

Medical treatment of intracerebral hemorrhage

Intracerebral hemorrhage (ICH) occurs as a result of bleeding into the brain parenchyma and formation of a focal hematoma. Treatment for ICH is primarily supportive, and outcome remains poor. Initial managemen...

S. Sacco, C. Marini, A. Carolei in Neurological Sciences (2004)

Article

Central nervous system vasculitis

Vasculitis is an inflammation of the vessel wall. It may be either primary or secondary. Primary vasculitis includes systemic vasculitis (large, medium, and small-vessel vasculitis) and localized vasculitis (...

A. Carolei, S. Sacco in Neurological Sciences (2003)

Article

Effects of 3,4-dihydroxybenzoic acid on root membrane potential in micropropagated tobacco plants

In order to understand the mechanism of action of the phenolic compound 3,4-dihydroxybenzoic acid, we tested its effect on tobacco root membrane potential. Tobacco root segments, excised from micropropagated p...

M. Mucciarelli, S. Sacco, M. Gallino, M. Maffei in Plant Cell, Tissue and Organ Culture (2000)

Article

Membrane potential hyperpolarisation in vesicular arbuscular mycorrhizae ofAllium porrum L.: a non-nutritional long-distance effect of the fungus

Variations in membrane potential difference (PD) were observed between root cortical cells ofAllium porrum plants, uninfected and infected withGlomus E3: cell membrane potential was constantly hyperpolarised in t...

M. Fieschi, G. Alloatti, S. Sacco, G. Berta in Protoplasma (1992)