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  1. No Access

    Article

    Pharmacokinetics of oral entacapone after frequent multiple dosing and effects on levodopa disposition

    Objective: Entacapone is a peripherally acting catechol O-methyltransferase (COMT) inhibitor used as an adjunct to each daily levodopa/dopa decarboxylase (DDC) inhibitor dose in the trea...

    J. Rouru, A. Gordin, R. Huupponen, S. Huhtala… in European Journal of Clinical Pharmacology (1999)

  2. No Access

    Article

    A double-blind study of MPV-2213ad, a novel aromatase inhibitor, in healthy male subjects

    Objective: Novel aromatase inhibitors are developed with requirements of high potency and selectivity for the aromatase enzyme. The hormonal effects of a new, non-steroidal competitive i...

    O. Ahokoski, K. Irjala, S. Huhtala… in European Journal of Clinical Pharmacology (1999)