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Open AccessMatrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
Increased matrix rigidity associated with the fibrotic reaction is documented to stimulate intracellular signalling pathways that promote cancer cell survival and tumour growth. Pancreatic cancer is one of the...
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Article
Open AccessMutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion
Tumour-derived mutant p53 proteins promote invasion, in part, by enhancing Rab coupling protein (RCP)-dependent receptor recycling. Here we identified MET as an RCP-binding protein and showed that mutant p53 p...
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Article
Socio-Demographic Characteristics of Children Infested with Community Acquired Scabies in Densely Populated Residential Institutions in Dhaka, Bangladesh
Background: Outbreaks of scabies in residential institutions is not reported so far particularly on socio-economic consequences.