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  1. Article

    Open Access

    Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

    Increased matrix rigidity associated with the fibrotic reaction is documented to stimulate intracellular signalling pathways that promote cancer cell survival and tumour growth. Pancreatic cancer is one of the...

    A J Rice, E Cortes, D Lachowski, B C H Cheung, S A Karim, J P Morton… in Oncogenesis (2017)

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