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  1. No Access

    Article

    Prognostic impact of FOXF1 polymorphisms in gastric cancer patients

    A recent genome-wide association study identified seven single-nucleotide polymorphisms (SNPs) in region 16q24, near the Forkhead box-F1 (FOXF1) gene, which confer susceptibility to esophageal adenocarcinoma. We ...

    S Matsusaka, A H Wu, S Cao, D L Hanna, K Chin, D Yang in The Pharmacogenomics Journal (2018)

  2. No Access

    Chapter and Conference Paper

    Performance of over 100 W HVM LPP-EUV Light Source

    light source is widely accepted to be the most promising solution for the 13.5 nm high power light source for high volume manufacturing (HVM) EUV lithography. We have been develo** LPP systems using CO2 lase...

    S. Okazaki, H. Nakarai, T. Abe, K. M. Nowak, Y. Kawasuji, H. Tanaka in X-Ray Lasers 2016 (2018)

  3. No Access

    Article

    A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials

    The Hippo pathway is involved in colorectal cancer (CRC) development and progression. The Hippo regulator Rassf1a is also involved in the Ras signaling cascade. In this work, we tested single nucleotide polymo...

    A Sebio, S Stintzing, V Heinemann, Y Sunakawa, W Zhang in The Pharmacogenomics Journal (2018)

  4. No Access

    Article

    Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients

    Using approved methods, circulating tumor cells (CTCs) are only isolated from blood in 30%–50% of metastatic colorectal cancer (mCRC) patients. We previously validated a technique to isolate circulating tumor ...

    Y Ning, W Zhang, D L Hanna, D Yang, S Okazaki, M D Berger in The Pharmacogenomics Journal (2018)

  5. No Access

    Article

    Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer

    Immunomodulator-targeting therapies are under development in gastric cancer (GC). However, the role of genes modulating anti-tumor immunity in GC remains poorly understood. We investigated the association of v...

    Y Sunakawa, S Cao, N B Volz, M D Berger, D Yang, A Parekh in The Pharmacogenomics Journal (2017)

  6. No Access

    Article

    CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy

    We analyzed associations between CXCR4/CXCL12 single-nucleotide polymorphisms and outcomes in metastatic colorectal cancer (mCRC) patients who underwent first-line bevacizumab-based chemotherapy. A total of 874 p...

    S Matsusaka, S Cao, D L Hanna, Y Sunakawa, M Ueno in The Pharmacogenomics Journal (2017)

  7. No Access

    Article

    Genetic variants associated with colorectal brain metastases susceptibility and survival

    Colorectal brain metastases (BM) are rare (1–2%) and a late-stage disease manifestation. Molecular mechanisms for BM development are not well understood. We tested whether variants within genes involved in ove...

    S Stremitzer, A S Berghoff, N B Volz, W Zhang, D Yang in The Pharmacogenomics Journal (2017)

  8. No Access

    Article

    Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer

    Estrogen has been shown not only to reduce the incidence of colorectal cancer but also gastric cancer (GC). Polymorphisms in estrogen receptor β gene, ESR2, correlate with colorectal cancer survival. To better un...

    Y Sunakawa, S Cao, M D Berger, S Matsusaka, D Yang, W Zhang in The Pharmacogenomics Journal (2017)

  9. No Access

    Article

    Preparation and electrical properties of sintered bodies composed of CrXMn1.5Co(1.0-X)Ni0.5O4 (0 ≦ X ≦ 0.42) with a cubic spinel structure

    Preparation and electrical properties of sintered bodies consisting of monophase cubic spinel oxides, CrXMn1.5Co(1.0-X)Ni0.5O4 (0 ≦ X ≦ 0.42), were investigated. Specimens with compositions within X = 0.42 were p...

    T. Yokoyama, A. Hirose, T. Meguro, D. Ito, Y. Koshiba in Journal of Electroceramics (2016)

  10. No Access

    Article

    Preparation and electrical properties of sintered bodies composed of Mn(2.25-X)FeXNi0.75O4 (0≦X≦2.25) with cubic spinel structure

    Preparation and electrical properties of sintered bodies consisting of monophase cubic spinel oxides, Mn(2.25-X)FeXNi0.75O4 (0≦X≦2.25), were investigated. Sintered bodies with monophase cubic spinel structure wer...

    T. Yokoyama, A. Yamazaki, T. Meguro, D. Ito, Y. Koshiba in Journal of Electroceramics (2016)

  11. No Access

    Article

    A New Fatigue Testing Machine for Investigating the Behavior of Small Shear-Mode Fatigue Cracks

    The investigation of the behavior of small shear-mode fatigue cracks in the high-cycle fatigue regime is essential to understand the mechanism of rolling-contact fatigue failures, such as flaking in bearings a...

    M. Endo, S. Okazaki, H. Matsunaga, S. Moriyama, K. Munaoka in Experimental Techniques (2016)

  12. No Access

    Article

    Preparation and electrical properties of sintered oxide composed of MnFeNiO4 with a cubic spinel structure

    The preparation and electrical properties of a sintered body consisting of cubic spinel oxide MnFeNiO4 were investigated. A sintered body with cubic spinel and NaCl-type oxides prepared at 1400 °C in Ar could be ...

    T. Yokoyama, T. Meguro, K. Kato, S. Okazaki, D. Ito in Journal of Electroceramics (2013)

  13. No Access

    Article

    Redox regulation in stem-like cancer cells by CD44 variant isoforms

    Increasing evidence indicates that several types of solid tumor are hierarchically organized and sustained by a distinct population of cancer stem cells (CSCs). CSCs possess enhanced mechanisms of protection f...

    O Nagano, S Okazaki, H Saya in Oncogene (2013)

  14. Article

    Common carotid intima-media thickness does not add to Framingham risk score in individuals with diabetes mellitus: the USE-IMT initiative

    The aim of this work was to investigate whether measurement of the mean common carotid intima-media thickness (CIMT) improves cardiovascular risk prediction in individuals with diabetes.

    H. M. den Ruijter, S. A. E. Peters, K. A. Groenewegen, T. J. Anderson in Diabetologia (2013)

  15. No Access

    Article

    Indentation technique for evaluation of master curve of creep compliance

    K. Sakaue, S. Okazaki, T. Ogawa in Experimental Techniques (2011)

  16. No Access

    Chapter and Conference Paper

    Symbiotic Roles and Transcriptional Analysis of the Type III Secretion System in Mesorhizobium loti

    Type III secretion systems (T3SS) have been identified in a number of rhizobia and were shown to affect symbiosis with legumes. For further exploitation of rhizobial T3SS, we analyzed Mesorhizobium loti MAFF30309...

    S. Okazaki, S. Okabe, S. Zehner, M. Göttfert in Biological Nitrogen Fixation: Towards Pove… (2008)

  17. No Access

    Chapter and Conference Paper

    Characterization of Bradyrhizobium elkanii Type III Secretion System

    Type III secretion systems (T3SS) have been identified in a number of rhizobia and were shown to affect symbiosis with legumes. The genes encoding the conserved core of the T3SS (rhc; rhizobium conserved) are hig...

    S. Okazaki, S. Zehner, K. Lang, M. Göttfert in Biological Nitrogen Fixation: Towards Pove… (2008)

  18. No Access

    Chapter and Conference Paper

    Energetic Proton and Deuteron Generation from a Microporous Polytetrafluoroethylene Film with Deuterated Polystyrene using a 2.4-TW Table-Top Laser

    Protons and deuterons over 1 MeV in energy were generated by 2.4-TW, 50-fs, 10-Hz laser pulses interacting with a film target. In particular, microporous polytetrafluoroethylene film infiltrated with deuterate...

    H. Takahashi, S. Okihara, S. Ohsuka, M. Fujimoto, S. Okazaki in Ultrafast Phenomena XIV (2005)

  19. No Access

    Chapter and Conference Paper

    Poster Summaries

    Kang Lihua, Jiang Yegen, Ma Haibin in Biological Nitrogen Fixation, Sustainable … (2005)

  20. No Access

    Chapter

    Near-Field Imaging of Molecules and Thin Films

    Characterization of materials on a nanometer scale becomes more important and indispensable year by year [1]. This is due to the development of new materials whose properties and functions are related to the s...

    M. Fujihira, S. Itoh, A. Takahara, O. Karthaus, S. Okazaki, K. Kajikawa in Nano-Optics (2002)

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