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  1. No Access

    Article

    Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer

    Immunomodulator-targeting therapies are under development in gastric cancer (GC). However, the role of genes modulating anti-tumor immunity in GC remains poorly understood. We investigated the association of v...

    Y Sunakawa, S Cao, N B Volz, M D Berger, D Yang, A Parekh… in The Pharmacogenomics Journal (2017)

  2. No Access

    Article

    Genetic variants associated with colorectal brain metastases susceptibility and survival

    Colorectal brain metastases (BM) are rare (1–2%) and a late-stage disease manifestation. Molecular mechanisms for BM development are not well understood. We tested whether variants within genes involved in ove...

    S Stremitzer, A S Berghoff, N B Volz, W Zhang, D Yang… in The Pharmacogenomics Journal (2017)

  3. No Access

    Article

    Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer

    Pericytes are crucial for angiogenesis. The impact of pericyte function to bevacizumab efficacy in mCRC treatment has not been comprehensively examined. This retrospective study investigated germline polymorph...

    N B Volz, S Stintzing, W Zhang, D Yang, Y Ning, T Wakatsuki… in The Pharmacogenomics Journal (2015)