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Article
Open AccessThe impact of COVID-19 on the diagnosis and treatment of HCC: analysis of a nationwide registry for advanced liver diseases (REAL)
The number of cancer cases diagnosed during the coronavirus disease 2019 (COVID-19) pandemic has decreased. This study investigated the impact of the pandemic on the clinical practice of hepatocellular carcino...
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Article
Open AccessDevelopment of a transformer model for predicting the prognosis of patients with hepatocellular carcinoma after radiofrequency ablation
Radiofrequency ablation (RFA) is a widely accepted, minimally invasive treatment modality for patients with hepatocellular carcinoma (HCC). Accurate prognosis prediction is important to identify patients at hi...
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Article
Current status of primary liver cancer and decompensated cirrhosis in Japan: launch of a nationwide registry for advanced liver diseases (REAL)
We developed a nationwide database that stores data of patients with primary liver cancer (PLC) and decompensated cirrhosis (DC) on an admission basis.
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Article
Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma
Liquid biopsies, particularly those involving circulating tumor DNA (ctDNA), are rapidly emerging as a non-invasive alternative to tumor biopsies. However, clinical applications of ctDNA analysis in hepatocell...
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Article
Open AccessGeneration of Schubert polynomial series via nanometre-scale photoisomerization in photochromic single crystal and double-probe optical near-field measurements
Generation of irregular time series based on physical processes is indispensable in computing and artificial intelligence. In this report, we propose and demonstrate the generation of Schubert polynomials, whi...
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Article
Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are characterized by the accumulation of excess hepatic fat. However, in the progression from NASH to cirrhosis, hepatic fat is ...
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Article
Open AccessHepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes. Our aim was to investigate the relationship between NAFLD and impaired glucose metabolism in terms of insulin receptor substrate 1...
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Article
Open AccessAuthor Correction: Nanometre-scale pattern formation on the surface of a photochromic crystal by optical near-field induced photoisomerization
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessNanometre-scale pattern formation on the surface of a photochromic crystal by optical near-field induced photoisomerization
We observed nanometre-scale optical near-field induced photoisomerization on the surface of a photochromic diarylethene crystal via molecular structural changes using an optical near-field assisted atomic forc...
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Article
Estimation of polarization distribution on gold nanorods system from hierarchical features of optical near-field
To design optoelectronic functionalities in nanometer scale based on interactions of electronic system with optical near-fields, it is essential to evaluate the relationship between optical near-fields and the...
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Article
Nano-optical functionality based on local photoisomerization in photochromic single crystal
Towards the construction of functional devices and systems using optical near-field processes, we demonstrate the multivalent features in the path-branching phenomena in a photochromic single crystal observed ...
