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    Article

    Current status of primary liver cancer and decompensated cirrhosis in Japan: launch of a nationwide registry for advanced liver diseases (REAL)

    We developed a nationwide database that stores data of patients with primary liver cancer (PLC) and decompensated cirrhosis (DC) on an admission basis.

    Kazuya Okushin, Ryosuke Tateishi, Arata Takahashi in Journal of Gastroenterology (2022)

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    Article

    Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma

    Liquid biopsies, particularly those involving circulating tumor DNA (ctDNA), are rapidly emerging as a non-invasive alternative to tumor biopsies. However, clinical applications of ctDNA analysis in hepatocell...

    Takuma Nakatsuka, Hayato Nakagawa, Yuki Hayata, Taijiro Wake in Journal of Gastroenterology (2021)

  3. No Access

    Article

    Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients

    Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are characterized by the accumulation of excess hepatic fat. However, in the progression from NASH to cirrhosis, hepatic fat is ...

    Kenichiro Enooku, Takeya Tsutsumi, Mayuko Kondo in Journal of Gastroenterology (2020)

  4. Article

    Open Access

    Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients

    Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes. Our aim was to investigate the relationship between NAFLD and impaired glucose metabolism in terms of insulin receptor substrate 1...

    Kenichiro Enooku, Mayuko Kondo, Naoto Fujiwara in Journal of Gastroenterology (2018)