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Article
Pharmacokinetics of oxycodone hydrochloride and three of its metabolites after intravenous administration in Chinese patients with pain
The aim of this study is to evaluate the pharmacokinetic profile of oxycodone and three of its metabolites, noroxycodone, oxymorphone and noroxymorphone after intravenous administration in Chinese patients wit...
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Article
ARK5 is associated with the invasive and metastatic potential of human breast cancer cells
To investigate the effects of Akt/ARK5 pathways on the metastatic potential of human breast cancer cells.
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Article
Simultaneous Determination of Hydrocodone, and Its Two Metabolites in Human Plasma by HPLC–MS–MS
A rapid, sensitive and specific assay method has been developed to simultaneously determine human plasma concentrations of hydrocodone and its metabolites, norhydrocodone, hydromorphone, using high-performance...
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Article
Bioanalysis of Cepharanthine by LC–ESI–MS–MS and Its Application to Pharmacokinetic Studies
A sensitive liquid chromatography–electrospray ionization–tandem mass spectrometry (LC–ESI–MS–MS) method was developed and validated for the quantification of cepharanthine (CEP) in beagle dog plasma. The chro...