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Chapter and Conference Paper
Centrality Speeds the Subgraph Isomorphism Search Up in Target Aware Contexts
The subgraph isomorphism (SubGI) problem is known to be a NP-Complete problem. Several methodologies use heuristic approaches to solve it, differing into the strategy to search the occurrences of a graph into ...
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Chapter and Conference Paper
On the Simulation and Automatic Parametrization of Metabolic Networks Through Electronic Design Automation
This work presents a platform for the modelling, simulation and automatic parametrization of semi-quantitative metabolic networks. Starting from a network modelled through Petri Nets (PN) and represented in SB...
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Chapter and Conference Paper
A Reliable Method to Remove Batch Effects Maintaining Group Differences in Lymphoma Methylation Case Study
The amount of biological data is increasing and their analysis is becoming one of the most challenging topics in the information sciences. Before starting the analysis it is important to remove unwanted variab...
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Article
Fast analytical methods for finding significant labeled graph motifs
Network motif discovery is the problem of finding subgraphs of a network that occur more frequently than expected, according to some reasonable null hypothesis. Such subgraphs may indicate small scale interact...
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Chapter
gLabTrie: A Data Structure for Motif Discovery with Constraints
Motif discovery is the problem of finding subgraphs of a network that appear surprisingly often. Each such subgraph may indicate a small-scale interaction feature in applications ranging from a genomic interac...
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Chapter and Conference Paper
Dynamic Modeling and Simulation of Leukocyte Integrin Activation through an Electronic Design Automation Framework
Model development and analysis of biological systems is recognized as a key requirement for integrating in-vitro and in-vivo experimental data. In-silico simulations of a biochemical model allows one to test d...
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Chapter
Computational Approaches to RNAi and Gene Silencing
The discovery of small regulatory RNAs in the past few years has deeply changed the RNA molecular biology, revealing more complex pathways involved in the regulation of gene expression and in the defense of th...
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Chapter and Conference Paper
Business Process Model Retrieval Based on Graph Indexing Method
Nowadays, business process reuse is very important and necessary inside large organizations that continually increase their process collections. Therefore, an efficient system to manage and search for concrete...
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Chapter and Conference Paper
MySQL Data Mining: Extending MySQL to Support Data Mining Primitives (Demo)
The development of predictive applications built on top of knowledge bases is rapidly growing, therefore database systems, especially the commercial ones, are boosting with native data mining analytical tools....
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Chapter and Conference Paper
An Efficient Duplicate Record Detection Using q-Grams Array Inverted Index
Duplicate record detection is a crucial task for data cleaning process in data warehouse systems. Many approaches have been presented to address this problem: some of these rely on the accuracy of the resulted...
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Chapter and Conference Paper
BitCube: A Bottom-Up Cubing Engineering
Enhancing on line analytical processing through efficient cube computation plays a key role in Data Warehouse management. Hashing, grou** and mining techniques are commonly used to improve cube pre-computati...
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Chapter and Conference Paper
Multiple-Winners Randomized Tournaments with Consensus for Optimization Problems in Generic Metric Spaces
Extensions of the randomized tournaments techniques introduced in [6,7] to approximate solutions of 1-median and diameter computation of finite subsets of general metric spaces are proposed. In the linear algo...
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Chapter
Efficient Boundary Values Generation in General Metric Spaces for Software Component Testing
One of the most classical and successful software testing strategies is that of testing boundary values in the input domain (Reid 1997). In this paper we introduce a notion of boundary values for a finite subs...
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Chapter and Conference Paper
P- \( \mathcal{S}\mathcal{H}\mathcal{O}\mathcal{Q} \) (D): A Probabilistic Extension of \( \mathcal{S}\mathcal{H}\mathcal{O}\mathcal{Q} \) (D) for Probabilistic Ontologies in the Semantic Web
Ontologies play a central role in the development of the semantic web, as they provide precise definitions of shared terms in web resources. One important web ontology language is DAML+OIL; it has a formal sem...