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Article
Open AccessZinc fever in a painter and varnisher: a case report
Zinc fever is well described in medical literature, particularly in workers after handling zinc-containing materials at high temperatures e.g., in the welding of hot-dip galvanized steel sheets. It is not know...
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Article
Open AccessReply on the comments of Ulla Vogel and colleagues on their recently published paper entitled “Re-evaluation of the occupational exposure limit for ZnO is warranted. Comments on ‘Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?’ by Christian Monsé et al.”
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Article
Open AccessSystemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?
Exposure to airborne substances such as gases, vapours, and particles remains a relevant health risk in many workplaces. A current topic and cause for discussion is the investigation of the health effects of p...
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Article
Open AccessNo inflammatory effects after acute inhalation of barium sulfate particles in human volunteers
Most threshold limit values are based on animal experiments. Often, the question remains whether these data reflect the situation in humans. As part of a series of investigations in our exposure lab, this stud...
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Article
Open AccessHealth effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers
Inhalation of ZnO particles can cause inflammation of the airways and metal fume fever. It is unclear if different sizes of the particles alter these effects. However, various studies report higher biological ...
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Article
Open AccessHeart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults
Exposure to airborne zinc oxide (ZnO) particles occurs in many industrial processes, especially in galvanizing and welding. Systemic inflammation after experimental inhalation of ZnO particles has been demonst...
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Chapter
Whole Blood Assay as a Tool to Describe the Effects of Zinc Oxide Exposure on Innate Immunity
Inhalation of high concentrations of zinc oxide (ZnO) particles may cause metal fume fever. A useful tool to characterize the reactivity of innate immune cells of an individual, e.g., after in vivo exposure, i...
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Article
Open AccessAirway inflammation after inhalation of nano-sized zinc oxide particles in human volunteers
Workers in the zinc production and processing of galvanized sheet steel are exposed to a complex mixture of particles and gases, including zinc oxide (ZnO) that can affect human health. We aimed to study the e...
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Article
Non-invasive tools beyond lung function before and after specific inhalation challenges for diagnosing occupational asthma
Increases of fractional exhaled nitric oxide (FeNO), sputum eosinophils, and methacholine responsiveness have been described after specific inhalation challenges (SIC) with occupational allergens, but limited ...
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Article
An increase of fractional exhaled nitric oxide after specific inhalation challenge is highly predictive of occupational asthma
An increase of fractional exhaled nitric oxide (FeNO) has been described after specific inhalation challenges (SICs) with occupational allergens, but the clinical role of FeNO measurements before and after SIC...
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Article
Open AccessConcentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers
Inhalation of high concentrations of zinc oxide particles (ZnO) may cause metal fume fever. In an earlier human inhalation study, no effects were observed after exposure to ZnO concentrations of 0.5 mg/m3. Furthe...
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Chapter
Cell Activation and Cytokine Release Ex Vivo: Estimation of Reproducibility of the Whole-Blood Assay with Fresh Human Blood
The whole-blood assay (WBA) with human fresh blood may provide insight into the features of an individual’s innate immunity. To assess this, ex vivo cytokine release is measured after stimulation of whole bloo...
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Article
Kurzfassung der AWMF-Leitlinie medizinisch klinische Diagnostik bei Schimmelpilzexposition in Innenräumen
Die von der Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin (GHUP) federführend erstellte Leitlinie „Medizinisch klinische Diagnostik bei Schimmelpilzexposition in Innenräumen“ ist Gegenstand des ...
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Article
Open AccessAbridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure
This article is an abridged version of the AWMF mould guideline “Medical clinical diagnostics of indoor mould exposure” presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Prev...
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Article
Medical surveillance and long-term prognosis of occupational allergy due to platinum salts
Medical surveillance of workers in precious metals refineries and catalyst production plants is well established in many countries as a measure to prevent occupational asthma due to platinum (Pt) salts. It was...
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Chapter
Serial Measurements of Exhaled Nitric Oxide at Work and at Home: A New Tool for the Diagnosis of Occupational Asthma
Whereas serial measurements of lung function at work and at home are a well-known diagnostic tool for the diagnosis of occupational asthma (OA), little is known about the serial measurements of non-invasive pa...
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Article
Exposure assessment of potash miners at elevated CO2 levels
In a potash mine in the center of Germany, stationary measurements 40 cm above ground level have revealed occasional increases in the carbon dioxide (CO2) levels that exceed the 0.5 vol.% German occupational expo...
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Chapter and Conference Paper
Occupational Non-immediate Type Allergic Asthma due to Ammonium Persulfate
While numerous cases of immediate-type occupational asthma due to persulfates with positive skin prick test reactions to ammonium persulfate are well documented, few non-immediate type reactions have been desc...
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Article
Irritative effects of vapours and aerosols of bitumen on the airways assessed by non-invasive methods
Irritative effects caused by vapours and aerosols of bitumen were assessed by non-invasive methods including spirometry, nasal lavage fluid (NALF) and induced sputum (IS) in a cross-shift study comparing 320 b...
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Article
Open AccessElimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies
Isocyanates are some of the leading occupational causes of respiratory disorders, predominantly asthma. Adequate exposure monitoring may recognize risk factors and help to prevent the onset or aggravation of t...
