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Article
Open AccessHeart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults
Exposure to airborne zinc oxide (ZnO) particles occurs in many industrial processes, especially in galvanizing and welding. Systemic inflammation after experimental inhalation of ZnO particles has been demonst...
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Article
Open AccessAirway inflammation after inhalation of nano-sized zinc oxide particles in human volunteers
Workers in the zinc production and processing of galvanized sheet steel are exposed to a complex mixture of particles and gases, including zinc oxide (ZnO) that can affect human health. We aimed to study the e...
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Article
Non-invasive tools beyond lung function before and after specific inhalation challenges for diagnosing occupational asthma
Increases of fractional exhaled nitric oxide (FeNO), sputum eosinophils, and methacholine responsiveness have been described after specific inhalation challenges (SIC) with occupational allergens, but limited ...
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Article
An increase of fractional exhaled nitric oxide after specific inhalation challenge is highly predictive of occupational asthma
An increase of fractional exhaled nitric oxide (FeNO) has been described after specific inhalation challenges (SICs) with occupational allergens, but the clinical role of FeNO measurements before and after SIC...
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Article
Open AccessConcentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers
Inhalation of high concentrations of zinc oxide particles (ZnO) may cause metal fume fever. In an earlier human inhalation study, no effects were observed after exposure to ZnO concentrations of 0.5 mg/m3. Furthe...
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Cell Activation and Cytokine Release Ex Vivo: Estimation of Reproducibility of the Whole-Blood Assay with Fresh Human Blood
The whole-blood assay (WBA) with human fresh blood may provide insight into the features of an individual’s innate immunity. To assess this, ex vivo cytokine release is measured after stimulation of whole bloo...
