Page
%P
-
Article
Circumcision Status Regret and Satisfaction: Findings of a US National Survey
There is an increasing movement to suggest the practice of newborn circumcision causes significant physical and emotional harm. Previous studies have provided evidence that circumcision can decrease the transm...
-
Article
Cardiovascular Imaging Databases: Building Machine Learning Algorithms for Regenerative Medicine
Myocardial regeneration is a promising alternative to heart transplantation, but the ideal stem cell type remains unknown due to conflicting results in clinical trials. Trial discrepancies may be addressed by ...
-
Article
Meat Allergy: A Ticking Time Bomb
Food allergies are relatively prevalent, but mammalian meat allergy remains uncommon and represents an important, potentially acute healthcare risk. This risk is partly because both clinicians and the public l...
-
Article
Open AccessA case of congenital ureteral atresia causing rare upper and lower urinary tract manifestations in a puppy: a case report
Ureteral atresia is the congenital absence of a ureteral opening, resulting in a blind-ended ureter that fails to terminate at the urinary bladder. Consequently, severe hydroureter and hydronephrosis occur ips...
-
Article
Quality Versus Costs Related to Gastrointestinal Surgery: Disentangling the Value Proposition
There has been a dramatic increase in worldwide health care spending over the last several decades. Operative procedures and perioperative care in the USA represent some of the most expensive episodes per pati...
-
Article
Open AccessStrategies to enable large-scale proteomics for reproducible research
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and de...
-
Article
Open AccessA pivotal role for Interferon-α receptor-1 in neuronal injury induced by HIV-1
HIV-1 infection remains a major public health concern despite effective combination antiretroviral therapy (cART). The virus enters the central nervous system (CNS) early in infection and continues to cause HI...
-
Article
Predicting history
Can events be accurately described as historic at the time they are happening? Claims of this sort are in effect predictions about the evaluations of future historians; that is, that they will regard the event...
-
Article
Robust network pricing and system optimization under combined long-term stochasticity and elasticity of travel demand
Network pricing serves as an instrument for congestion management, however, agencies and planners often encounter problems of estimating appropriate toll prices. Tolls are commonly estimated for a single-point...
-
Article
Without-replacement sampling for particle methods on finite state spaces
Combinatorial estimation is a new area of application for sequential Monte Carlo methods. We use ideas from sampling theory to introduce new without-replacement sampling methods in such discrete settings. Thes...
-
Chapter and Conference Paper
Smart and Precision Polyhouse Farming Using Visible Light Communication and Internet of Things
Recently, Polyhouse farming has taken the place of traditional farming. This technique reduces dependency on rainfall and dramatically changing environmental conditions and makes the optimum use of land and wa...
-
Article
Congenital subaxial cervical subluxation presenting as a bilateral Erb’s palsy: surgical management, rehabilitation, and outcome
Subaxial spine injuries during infancy are uncommon.
-
Article
Open AccessAntibiotic association in patients presented to ED with diarrhoea found positive for C. difficile infection-A retrospective study
-
Book
-
Chapter
Composition and Structure
Lipid nanoparticles, including solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), lipid-drug conjugates (LDC) and polymer-lipid hybrid nanoparticles (PLN), are colloidal carriers with a lipi...
-
Chapter
Introduction
Highly potent, but poorly water-soluble, drug candidates are common outcomes of lead optimization and other such drug discovery programmes. Poor drug solubility presents several challenges including reduced bi...
-
Chapter
Characterization
Lipid nanoparticles are known to present three features—a solid nature, lipid matrix and colloidal (or smaller) particle size. These features are theorized to impart controlled drug release, biocompatibility a...
-
Chapter
Production Techniques
Besides composition and structure, an important factor which influences the performance and characteristics of lipid nanoparticles is their production method, and a variety of production techniques have been i...
-
Chapter
Physicochemical Stability
Recent advances in lipid nanoparticle research suggest that colloidal carriers have great potential for administration of drug molecules. The use of physiological lipids in their matrices presents the advantag...
-
Article
Computationally efficient map construction in the presence of segregation distortion
We present a novel estimator for map construction in the presence of segregation distortion which is highly computationally efficient. For multi-parental designs this estimator outperforms meth...
